In this week's episode, Brett and Martin talk to Adjunct Assistant Prof Dr Kalisvar Marimuthu, who is currently a senior consultant in Infectious Diseases at the National Centre for Infectious Diseases and Tan Tock Seng Hospital, Singapore. We discuss his recent paper that notes that over 50% of transmissions occurring in healthcare result from plasmid and not colonal spread. Traditional IPC interventions seem to work for clonal transmission, however new thinking is required to tackle the problems of plasmids.
Papers we discuss are:
1. Marimuthu K, Venkatachalam I, Koh V et al. Whole genome sequencing reveals hidden transmission of carbapenemase-producing Enterobacterales. Nat Commun 2022; 13: 3052. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160272/
2. Ng DHL, Marimuthu K, Lee JJ et al. Environmental colonization and onward clonal transmission of carbapenem-resistant Acinetobacter baumannii (CRAB) in a medical intensive care unit: the case for environmental hygiene. Antimicrob Resist Infect Control 2018; 7: 51. https://aricjournal.biomedcentral.com/articles/10.1186/s13756-018-0343-z
Visualising infection transmission using genomics
Investigating a unique CPE strain outbreak - a possible new place to look?
C. difficile in England is on the rise, but why? A sign of a system on the edge and could a new variant push it over?
What do C. difficile and HAP have in common - toilet plume??
A national CPE survey of healthcare workers knowledge and some interesting sink practices
90% Reduction in MRSA bacteraemia. Possible but patience is a virtue!
C. difficile: Disinfectants, attachment and strain variations
The 2023 End of Year/Christmas Special
If you could have anything in IPC, what would you want?
Would you be admitted to a room where a previous person was infected?
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Detection of pathogens in the neonatal ICU environment with Dr Ginny Moore
Preventing device-associated infections during a COVID-19 pandemic
Identifying healthcare cleaning research priorities in resource-limited settings
Sinks in ICU Patient Rooms. Lower numbers of sinks equals lower infection rates?
Future directions for surveillance
C. difficile and One Health with Prof Tom Riley
Saving time and increasing IPC efficiency using Robotic Process Automation
A CLEEN study chat and a rude interruption!
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