Taken from Lecture by Gerard Mullin, MD Johns Hopkins University School of Medicine for OMA 2018 conference in DC
Disruptions in Gut Microbiome are linked to range of chronic conditions
Child and Adult Obesity, Anxiety, Arthritis, Asthma, Autism, Autoimmune disorders, Cardiovascular*, Chronic fatigue, Chronic kidney disease, Depression, Diabetes (type 1 and type 2), Eczema and Most all OTHER IMMUNE ISSUES (i.e increase infections) *Fatty Liver, Fibromyalgia, Hypercholesterolemia, ITP, Metabolic Syndrome, Mood disorders, Multiple Sclerosis, Myoclonus dystonia, *Obesity, Oxalic kidney Stones, Parkinson’s Disease, Senile Dementia, etc
Gastrointestinal Gallstones, Colorectal Cancer, SIBO, Enteropathies, Hepatic Encephalopathy, *IBS, IBD, FMF, Gastric cancer and lymphoma, *Recurrent Clostridium difficile infection Non-GI
SO MANY MECHANISMS
One is increase gut permeability
You want a good mucosal layer in your GI tract to protect your body from pathogenic bacteria.
We actually know some of the strains of bacteria predispose to these diseases
Depending on the bacteria you have. One kind of bacteria (firmicutes) are more efficiently at breaking down food / fermenting foods and extracting calories. (tend towards weight gain)
Low carb AND low fat diets decrease firmicutes
High carb and high fat diet (SAD) increases firmicutes and decreases good bacteria.
Whole body chronic inflammation
Disruptions caused by
What to do about it
Too many options and benefits probably depend on your genetics.
Only take if you are also taking antibiotics or if you are treating something specifically (like h.pylori)
One reason Roux-en Y Gastric Bypass Surgery works because of changes in the microbiome.
You can still do low carb or keto healthily but not if you’re living on bacon.
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