Metastasis, when cancer cells leave the breast and spread to other sites in the body, is the major cause of mortality from breast cancer. The brain is one of the most common organs breast cancer invades, occurring in more than one third of patients with advanced breast cancer, up to 300,000 patients a year. The prognosis of cancer patients who develop brain metastasis is poor, with only 20 percent of patients surviving at one year.
For Dr. Priscilla Brastianos, a BCRF investigator since 2017, this cause hits close to home. Both her mother and grandmother died of metastatic breast cancer. That’s why she has dedicated her career to better understanding brain metastasis. As the Director of the Central Nervous System Metastasis Program & Assistant Professor of Medicine at Harvard Medical School and Massachusetts General Hospital, her research focuses on understanding the mechanisms driving metastatic disease to the brain. She is currently conducting studies to characterize the genetic and molecular profiles of brain metastasis compared to primary breast cancer with the goal of identifying potential targets for therapy and strategies to improve response to existing therapies.
How Diet and Lifestyle Influence Your Breast Cancer Risk with Dr. Graham Colditz
BCRF’s 2021 Boston Hot Pink Symposium
Artificial Intelligence and the Future of Breast Cancer Research with Dr. Connie Lehman
Breaking Down Personalized Diagnostics in Breast Cancer with Dr. Joshua LaBaer
Understanding Global Breast Cancer Disparities with Dr. Temidayo Fadelu
Unraveling the Mysteries of Inherited Gene Mutations with Dr. Ephrat Levy-Lahad
Perfecting and Personalizing Risk Assessment with Dr. Katherine Nathanson
New Approaches to Reducing Repeat Breast Cancer Surgeries with Dr. Mehra Golshan
Improving the Quality of Life for Breast Cancer Patients and Survivors with Professor Dame Lesley Fallowfield
Understanding Radiation Resistance and Barriers to Quality Care with Dr. Lori Pierce
Connecting the Dots Between Breast Cancer Risk and Obesity, with Dr. Vared Sterns
BCRF Symposium and Awards Luncheon 2020
Improving National and Global Racial Disparities in Breast Cancer Care with Dr. Funmi Olopade
A Closer Look at the Evolution of Breast Cancer Cells with Dr. Kornelia Polyak
Exploring the Many Intersections of Health Equity in Latin America with Dr. Jeffrey Weitzel
Closing the Gap in Breast Cancer Care with Dr. Mariana Chavez MacGregor
The Promise and Potential of Breast Cancer Vaccines with Dr. Karen Anderson
The Underlying Biology of Drug Resistance with Dr. Sarat Chandarlapaty
A Cross-disciplinary Approach to Breast Cancer Research with Dr. Antonio Wolff
Breast Cancer Care and COVID-19: From the Frontlines with Dr. Judy Garber
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