Authentic and Agentic with Jayson Manship

Eli Lilly supercomputer, Pentagon AI contracts and building custom apps

Host Jayson Manship records from a gaming convention in Louisville, Kentucky, to share the latest artificial intelligence news and his personal software experiments on this solo episode of Authentic and Agentic. Manship covers Eli Lilly's partnership with Nvidia to build a massive supercomputer in Indianapolis designed for drug discovery. He also breaks down the Pentagon's decision to sever ties with Anthropic over autonomous weapons concerns and sign a new contract with OpenAI. Additionally, Manship explores a Google patent for AI-generated landing pages and its potential impact on web publishers and e-commerce. In the second half of the show, Manship details his attempt to build a personal AI assistant using a Mac mini and the open-source agent OpenClaw. He warns listeners about the software's unpredictable behavior, security risks and high token costs. Manship concludes by recommending Anthropic's Claude desktop app for workflow automation and the Replit platform for building custom business applications, sharing how he built a staff scheduling app for his own company in less than 24 hours.

Congresswoman Erin Houchin on AI safety regulation and data center concerns

Host Jayson Manship explores the intersection of technology and politics on this episode of the Authentic and Agentic podcast. In the news segment, Manship breaks down a lawsuit regarding Instagram age verification, a standoff between Anthropic and the Pentagon over AI safeguards and the growing strain data centers place on local energy grids. Manship is then joined by U.S. Rep. Erin Houchin to discuss her legislative efforts to establish guardrails and protect children online. Houchin outlines four bills she helped author, including the Safe Bots Act and the Reset Act. She explains the need to raise the standard social media access age to 16 and mandate clear warnings for AI chatbots that simulate human relationships or encourage self-harm. The conversation also covers the global AI space race against China, the push for small modular nuclear reactors at Crane Naval Base to handle massive energy demands and how Silicon Valley CEOs are increasing their presence in Washington.

How Eli Lilly Is Scaling AI Across Drug Discovery, Manufacturing and Commercial Operations

At Eli Lilly’s corporate center in Indianapolis, Authentic and Agentic host Jayson Manship speaks with Tim Coleman, Lilly's Chief Technical Officer and Thomas Fuchs, Lilly's Chief AI Officer, about how the global pharmaceutical company made artificial intelligence a strategic priority. The discussion explores how leadership aligned around AI as a long-term transformation, not a short-term experiment. Coleman outlines three pillars that built Lilly’s foundation: experimentation, governance and education. From structured alpha and beta testing to executive education with Purdue University’s Daniels School of Business, the company focused on learning before scaling. Fuchs explains why machine learning is built on repeated failure and how Lilly’s decades of successful and failed experiments create a unique data advantage. The episode highlights applications across the pharmaceutical value chain, including molecular design, digital twins in manufacturing and internally developed AI models. The conversation also addresses executive sponsorship, AI governance, global regulation and the importance of education to remain competitive in the global AI race. For business leaders, the takeaway is clear: lean into your core strengths, focus on real value and ensure leadership engagement at the highest level. Authentic and Agentic is part of the IBJ Media Podcast Network and examines the human side of AI.

Super Bowl AI ads, ‘SaaS apocalypse’ and Indiana tech panel

Host Jayson Manship breaks down the impact of artificial intelligence on culture and the economy on this episode of Authentic and Agentic. Manship analyzes the 23% of Super Bowl commercials that used AI and the market selloff sparked by Anthropic’s new software capabilities. He also covers a Blizzard Entertainment union contract that limits unchecked automation. The episode includes a panel discussion from a TechPoint event at IU Health. Manship interviews Ian Andrews of Eli Lilly, Cameron Mueller of Data 317 and Kate Harrison of Innovate Map. The group debates the need for critical thinking skills in an AI world and explores how the technology affects entry-level talent.

AI Ethics, Human Formation and the Common Good

Meghan Sullivan and Adam Kronk join the podcast to examine the ethical challenges posed by artificial intelligence. Drawing from philosophy, education and social service work at the University of Notre Dame, they discuss how AI is changing the way people learn, work and understand human dignity. The episode introduces the Institute for Ethics in the Common Good and its DELTA framework, offering a human-centered approach to AI that emphasizes agency, truth and flourishing in a rapidly changing technological world.