What is the risk of AKI following contrast CT in septic patients?
The concept of contrast-induced nephropathy (CIN) came from a 1954 paper and has been widely taught over the last 60 years. However, recent studies have questioned the true incidence of CIN, and even whether it exists at all. There are in fact many robust RCTs[2,3] now showing no association between contrast administration and acute kidney injury (AKI). The earlier confusion seems to have arisen for several reasons:
Hinson JS, Al Jalbout N, Ehmann MR, Klein EY. Acute kidney injury following contrast media administration in the septic patient: a retrospective propensity-matched analysis. J Crit Care. 2019;51:111-116
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