Scientific Sense ® by Gill Eapen: Prof Trey Ideker is Professor of Medicine, Bioengineering and Computer Science at the University of California, San Diego. He directs the National Resource for Network Biology, and the Cancer Cell Map and Psychiatric Cell Map Initiatives.
A multi-scale map of cell structure fusing protein images and interactions. Nature. 2021 Nov 24. doi: 10.1038/s41586-021-04115 “We Might Not Know Half of What’s in Our Cells, New AI Technique Reveals Interpretation of cancer mutations using a multiscale map of protein systems. Science. 2021 A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity. A protein interaction landscape of breast cancer. Science. 2021 Oct;374(6563):eabf3066 “Studies Delve Deep into the Protein Machinery of Cancer Cells.” NCI (4 Nov 2021) “From COVID to cancer, gene-mapping tool could ‘revolutionize’ treatment“. SF Chronicle (2 Oc “Moonshot Project Aims to Understand and Beat Cancer Using Protein Maps“. Singularity Hub (5 Oct 2021) “Looking Beyond DNA to See Cancer with New Clarity,” Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Cancer Cell (2020), https://doi.org/10.1016/j.ccell.2020.09.014. PMID: 33096023. [PDF] [PubMed] Related Press: UCSD Health, AZoLifeSciences, Med India, Health IT Analytics and ScienceDaily. Quantitative Translation of Dog-to-Human Aging by Conserved Remodeling of the DNA Methylome. Cell Systems. 2020 Aug 26;11(2):176-185.e6. doi: 10.1016/j.cels.2020.06.006. Epub 2020 Jul 2. PMID: 32619550 [PDF] [PubMed] *Cover Article Related Press: Here’s a better way to convert dog years to human years, scientists say. Science Magazine (15 Nov 2019). See also: Scientific American, BBC, NPR, Washington Post, Discover Magazine, Smithsonian, New York Post, (and more) Identifying Epistasis in Cancer Genomes: A Delicate Affair. Cell. 2019 May 30;177(6):1375-1383. doi: 10.1016/j.cell.2019.05.005. Review. PMID: 31150618 [PDF] [PubMed] Using deep learning to model the hierarchical structure and function of a cell.* Nat Methods. 2018 Mar 5. doi: 10.1038/nmeth.4627. PMID: 29505029 [PDF] [PubMed] [Cover Art] *Cover article Please subscribe to this channel: https://www.youtube.com/c/ScientificSense?sub_confirmation=1
--- Send in a voice message: https://podcasters.spotify.com/pod/show/scientificsense/message Support this podcast: https://podcasters.spotify.com/pod/show/scientificsense/supportProf. Joel Bakan on the New Corporation
Prof. Chris Barrett on ‘Benevolent’ patent extensions, community forests, and crop yield estimation
Dr. Paul Heggarty on the history and progression of Indo-Europeans
Prof. Eugene Volokh of UCLA on freedom of speech for humans, organizations, and AI.
Prof. Mariassunta Giannetti on supply chains, market power, inflation and liquidity reallocation
Prof. Anthony LoSasso on healthcare providers, payors, prices and markets
Prof. Jeffrey Pinto of Penn State on Covid reality & Normalization of Deviance in Project Management
Mr. Ashwin Ramaswami, senatorial candidate in Georgia on the opportunities for the next generation
Prof Annamaria Lusardi of Stanford University on the importance of financial literacy
Priyanca Ford on the promises and challenges of fusion energy
Prof. Moran Cerf of Columbia Business School on humanity, AI and decision-making
Prof. György Buzsáki of NYU on the Cognition from the Body-Brain Partnership
Prof. Ilana Redstone of the University of Illinois at Urbana-Champaign on the Certainty Trap.
Prof. Linda-Gail Bekker of the University of Cape Town on the prevalence of HIV and other diseases
Prof. Cass Sunstein of Harvard University on the power of noticing what was always there
Prof. Monica L. Smith of UCLA on the Fundamentals of the State
Prof. Claudia de Rham of Imperial College on Gravity.
Prof. Susan Goldin-Meadow of the University of Chicago on gestures and language
Prof. Robin Chazdon on forest regeneration and climatic impacts
Prof. Francine Blau of Cornell University on Gender Inequality in the Labor Market
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