August 2022
The papers behind the pod:
It’s the third Thursday of August, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce, and refine the use of animals in research. Follow this link for the full transcript: https://nc3rs.org.uk/3-minute-3rs-podcast-august-2022-transcript
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Assessing enrichment, consolidating animal research guidance and understanding mouse aggression
Replacing animal-derived reagents, simulating in utero microinjections and clicker training for mouse gait assessment
Kidney organoid vascularisation, implementing masking and quantitatively assessing experiment severity
Assessing pain, living systematic reviews and inducing focal hypoxia in human neurons
Statistical planning, human cell cultures for toxoplasma and preventing boredom in laboratory rodents
Larger species refinement special: improving the welfare of rabbits, non-human primates and sheep
3Rs Prize: A benchtop organ-on-a-chip fabrication method and an ex vivo model of focal demyelination
Humane intervention points, virtual gene knockout and ex vivo brain slices for Parkinson's research
Microbrains for neurotoxicity testing, improved experimental design, and post-op severity assessment
How environment and experimenter affect reproducibility, ex vivo adipocytes, and rodent enrichment
Replacement methods for drug development, toxicology testing and cardiovascular research
Issues with conventional rodent housing, playpens for rats, and using sleep to assess welfare
Reproducibility in cancer biology, training rats for refined fMRI, and playpens for mice
Refining anaesthesia and euthanasia for zebrafish and mice
Discover the winners of this year's Global AAALAC/IQ Awards
People and strategies behind 3Rs science: compassion fatigue, culture of care and systematic reviews
3 Minute 3Rs September 2021
3 Minute 3Rs August 2021
3 Minute 3Rs July 2021
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