With a history extending back millennia, with a biology that leads to permanent disability for tens of millions of people globally, and with a bacterial endosymbiont that may prove to be its Achilles heel, the filarial parasites that cause lymphatic filariasis are quite the complex creatures. In this episode, we explore the intricacies of this neglected tropical disease - also known as elephantiasis. We start by examining its complicated ecology involving many mosquito and parasite species, before moving on to its tricky biology where we finally answer the age-old question, “What is the lymphatic system anyway?”. Next, we move on to the convoluted history of lymphatic filariasis, where it holds the distinction of being the first disease recognized as mosquito-borne. We wrap up the episode with a look at its present global status, grappling with some current figures on the tremendous global burden of this disease and investigating some exciting treatment developments that will hopefully bring relief to the hundreds of millions of people at risk of developing this debilitating disease.
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Ep 138 Fever: Take it to the limit
Special Episode: Dr. Deirdre Cooper Owens & Medical Bondage
Ep 137 ME/CFS: What’s in a name? (A lot, actually)
Ep 136 Long Covid: A long time coming
Ep 135 Menopause is whatever you want it to be
Ep 134 Tonsils: Underestimated and underappreciated
Ep 133 Parvoviruses: Who let the dogs (and their viruses) out?
Ep 132 Osteogenesis Imperfecta: All bones about it
Ep 131 Parkinson’s Disease: Dopamine & discoveries
Ep 130 Cocoliztli: We do love a salty dish
Ep 128 Skin Cancer: We love and fear the sun
Ep 127 Bhopal: The 1984 Union Carbide Disaster
Ep 126 Migraine: A Cacophony in Four Movements
Ep 125 Blastomycosis: How fungus became amongus
Ep 124 The full spectrum of color vision deficiency
Ep 123 Hand, Foot, and Mouth (and Butt?) Disease
Ep 122 Asthma: A phlegmy episode
Special Episode: Ed Yong & An Immense World
Ep 121 Tularemia: Hare today, gone tomorrow
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