TWiV 1289: Building a better hepatitis B trap

TWiV explains how the dengue virus protein NS1 alters Aedes aegypti midgut permeability and favors virus dissemination, and achieving a complete hepatitis B virus cure in chronic hepatitis B virus-infected humanized mice by using a capsid assembly modulator.

Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli

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Links for this episode

• Support science education at MicrobeTV
• ASV 2026
• Positions in Rosenfeld Lab (email)
• Dengue virus NS1 alters mosquito midgut permeability (mBio)
• HBV cure with a capsid assembly modulator (Cell Host Microbe)
• Letters read on TWiV 1289
• Timestamps by Jolene Ramsey. Thanks!

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Angela – How hibernating bears maintain muscle mass
Alan – The flood of Chinese grad students in the 2000s was a boon to US students.
Vincent – Feynman Lectures on Physics

Listener Picks

David – Stewart Cheifet, Host of TV’s ‘Computer Chronicles,’ Dies at 87
Charles – Last Year, and the Year to Come

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.