In this episode of the Vets First Podcast, hosts Dr. Levi Sowers and Brandon Rea interview Dr. Oliver Gramlich, a research health science specialist at the Iowa City VA Health Care System. He is also a research assistant professor in the Neuroscience and Pharmacology Program at the University of Iowa.
Dr. Gramlich was born in Frankfurt, Germany, and went to graduate school at the University of Mines, where he was interested in biology and ophthalmology. After he obtained his PhD, he was recruited to the University of Iowa to work on glaucoma-related vision loss at the Department of Ophthalmology. This led him to become interested in many other vision-related diseases surrounding the optic nerve, such as multiple sclerosis and traumatic brain injury (TBI).
Throughout the beginning of the episode, Dr. Gramlich narrates his journey to neuro-ophthalmology research at the University of Iowa and his preclinical research at the VA. He discusses the importance of using animal models to translate physiological knowledge from experiments to human subjects. He later talks about the importance of the optic nerve in visual information transmission and elaborates about the physiological mechanisms and effects of various diseases such as glaucoma and multiple sclerosis.
In the second half of the episode, Dr. Gramlich discusses potential treatments for vision-related diseases. He then talks about his work regarding biomarkers of the visual system that relate to humans and describes potential ways to enhance recovery in patients dealing with optic neuritis. Dr. Gramlich shares his work with utilizing a combination of different diets and drugs to manipulate metabolic pathways in order to promote neuroprotective and anti-inflammatory effects to remedy optic nerve inflammation. Lastly, he describes his use of three-dimensional imaging to observe disease progression and resolution based on multiple variables and how this can directly apply to the clinical side of vision.
If you are a Veteran or you know a Veteran needing help with visual loss, contact the Visual Impairment Services Team coordinator at your nearest VA medical center or contact the Blind Rehabilitation Service Program by phone which can be found here. There are 13 Blind Rehabilitation Centers around the country, which can help with things like mobility, communication, and living with vision loss.
Louis Kolling: From the Army to Science, How an Army Veteran found a career in science
A Discussion with Neil Andrews From the Migraine Science Collaborative
Season 3 Episode 8: Understanding diabetes and vision loss: A walkthrough with Dr. Randy Kardon
Season 3 episode 4: Resilience and growth through traumatic vision loss: Tim Hornick
Season 3 Episode 2: Guiding the way to meaningful research for Veterans: Dr. Lina Kubli
Season 3 Episode 12: Building bridges in international veteran vision research: Dr. Renata Gomes and Bravo Victor
Season 3 Episode 3: Investigating visual disfunction in blast traumatic brain injury: Dr. Steven Fliesler
Season 3 episode 5: Providing support and community with sight loss: Dr. Laura Peters
Season 3 Episode 11: Advocating for Veterans and families with sight loss: Dr. Thomas Zampieri and the Blinded Veterans Association
Season 3 episode 9: Navigating life with glaucoma related vision loss: Liz Holmes
Season 3 Episode 7: Life and independence after diabetic vision loss: Loretta Phillips
Season 3 Episode 6: Connecting sight loss, TBI, the importance of building a care network: Dr. Eric Singman
Season 3 Episode 1: Introduction to season 3
Season 2 Bonus Episode – First-hand experience in the trenches of Covid-19: Dr. Alejandro Pezzulo
Season 2 Episode 7 – Perseverance through care and routine: Dr. Carolyn Turvey and Dr. Anne Sadler discuss research on depression and suicide risk with our Veterans
Season 2 Episode 2 – Not broken, just doing things differently: Director of Disability in Education for the Student Veterans of America, Dan Standage
Season 2 Episode 5 – Learning about drug use disorders from origin to treatment: Dr. Anthony Miller and Dr. John Wemmie
Season 2 Episode 1 – Kicking off Season 2 of the Vets First Podcast
Season 2 Episode 3 – Aiding vision-impaired Veterans through experience: Iowa City VA VIST Coordinator Keith Queen
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