Connecting Hearts: The Science and Stories of Congenital Heart Innovation

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A month of movement—across states, across continents, and across ideas—shapes this episode of Heart to Heart with Anna, where personal connection meets the frontiers of heart medicine. We begin with gratitude, travel, and family updates, then explore two breakthroughs shaping the future of congenital heart care: a major open-access study using whole-genome sequencing to forecast outcomes after CHD surgery, and nanotechnology that turns everyday implants into infection-resistant, tissue-regenerating tools.

CHD News Article Referenced:
“Genome sequencing is critical for forecasting outcomes following congenital cardiac surgery,” published in Nature Communications (open-access).
🔗 https://www.nature.com/articles/s41467-025-61625-0

Our guest, Tom Webster, has spent more than two decades showing that the tiniest details can change everything. By adding nanoscale textures to already-approved implant materials, his teams have helped more than 30,000 patients—without a single reported implant failure. Tom explains how these nanostructured surfaces reduce infection without antibiotics, encourage heart and vascular tissue to heal, and speed up regulatory approval by keeping the chemistry the same while transforming the surface.

Together, we explore cardiac patches that act like “Band-Aids for the heart,” vascular stents that resist clotting, and lessons learned from nature’s own antibacterial designs. We also talk about emerging strategies that combine nanomaterials with stem cells—guiding differentiation without drugs and anchoring cells exactly where the body needs repair. And we look ahead to implantable nanosensors that may one day send real-time data straight to your phone, giving families and clinicians a continuous picture of heart health far beyond today’s occasional lab tests.

If you’re curious how genetics, materials science, and continuous monitoring could personalize heart care for people living with CHD, this is the episode for you. Press play, share it with someone who needs hope grounded in evidence, and subscribe for more conversations like this. If this episode moved you, please leave a review and let us know which ideas you’d like us to explore next.

Have a question for Tom?
He welcomes inquiries from listeners who are curious about nanotechnology, innovation, and heart health. Please send your question to Anna@HeartToHeartWithAnna.com, and I will be happy to pass it along to him.

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