TWiV 1273: Myocarditis and mimicry

TWiV explains studies which reveal that Inhibition of CXCL10 and IFN-γ mitgates myocarditis associated with SARS-CoV-2 mRNA vaccination, and identification of a bacteriophage T7 protein that antagonizes the DNA restriction system of the host by mimicking B form DNA.

Hosts: Vincent Racaniello and Jolene Ramsey

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Links for this episode

• Support science education at MicrobeTV
• ASV 2026
• Understanding mRNA vaccine-associated myocarditis (Sci Transl Med)
• T7 protein overcomes DNA restriction of host (J Mol Biol)
• Structure of T7 protein that mimics DNA (Mol Cell)
• Letters read on TWiV 1283
• Timestamps by Jolene Ramsey. Thanks!

Weekly Picks

Jolene – Book series Dinosaur Therapy, Dinosaur Philosophy, & Dinosaur Friendship
Vincent – One Plus One Equals One: Symbiosis and the evolution of complex life by John Archibald

Listener Picks

Terry – Arcadia by Tom Stoppard
Greg – Charctic Interactive Sea Ice Graph | National Snow and Ice Data Center

Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.