The BSH Guidelines Official Podcast
Health & Fitness:Medicine
CNS lymphoma (CNSL) is associated with inferior outcomes, which may be attributed to several factors: poor CNS penetrance of chemotherapeutics, including RCHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone),1 impaired neurocognitive function and patient performance status (PS) contributing to increased treatment toxicity,2, 3 and recurrent genetic aberrations conferring treatment resistance.4-6 The rarity and heterogeneity of SCNSL also limits the evidence base for treatment recommendations, with poor outcomes potentially attributable at least in part to lack of optimised treatment protocols.
This good practice paper focuses on diffuse large B-cell lymphoma (DLBCL), the most common SCNSL subtype. It covers diagnostic and therapeutic aspects of care for the three SCNSL scenarios and multiply relapsed SCNSL. Treatment recommendations are framed by patient fitness and treatment intent.
Diagnosis and management of heparin-induced thrombocytopenia: Third edition
Diagnosis and management of marginal zone lymphomas
Guideline on the Investigation and management of a raised serum ferritin
Significant Haemoglobinopathies: a guideline for screening and diagnosis
Diagnosis and management of Mantle Cell Lymphoma
Investigation and management of the monoclonal gammopathy of undetermined significance (MGUS)
Guideline on the investigation and management of acute transfusion reactions
Haematological management of major haemorrhage
Anticoagulant management of pregnant individuals with mechanical heart valves
EHA 2022: The Use of Next-generation Sequencing in the Diagnosis of Rare Inherited Anaemias: A Joint BSH/EHA Good Practice Paper
Guidelines for thrombophilia testing
Good Practice Paper for management of older patients with frailty and acute myeloid leukaemia
Guideline for the first-line management of Classical Hodgkin Lymphoma
BSH ASM: Guidelines Session: GPP Cytomegalovirus serological testing in potential allogeneic haematopoietic stem cell transplant recipients
BSH ASM: Guidelines Session Presentation: Preoperative patient blood management during the SARS-CoV-2 pandemic
BSH ASM: Guidelines Session Presentation: Myelodysplastic syndromes
BSH ASM: Guidelines Session Presentation Diagnosis and Management of Waldenstrom Macroglobulinaemia
Guideline for the treatment of chronic lymphocytic leukaemia
The use of next-generation sequencing in the diagnosis of rare inherited anaemias: A Joint BSH/EHA Good Practice Paper
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