Advances in technology and computational power opened the doors to dissecting human genomic datasets and understanding the complex genetic interactions underlying disease. In this episode, Dr. Manolis Kellis discusses his recent paper with Dr. Tsai analyzing the transcriptomes of 48 postmortem Alzheimer’s Disease brain samples. Dr. Kellis is a Professor of Computer Science at MIT, the head of the MIT Computational Biology Group, the principal investigator of CSAIL (Computer Science and Artificial Intelligence Lab), and an Institute Member at the Broad Institute.
A hidden link between amino acid metabolism and peripheral neuropathy in diabetes
The AI model that’s building novel proteins
Countering antibiotic resistance using engineered bacteria
Healing Wounds Faster with the Body’s Own Motion
Fighting Cancer with a Cell-Based Vaccine
A Fireside Chat with Carolyn Bertozzi
Social media: the good, the bad and the hopeful
How preterm infants benefit from emotional connection
Arcade Neuro: brain cells in a dish learn to play Pong with Dr. Brett Kagan
A Fireside Chat with May-Britt Moser
At-home healthcare: monitoring Parkinson’s disease with radio waves
The chronic disease caused by a common virus
A telescope to look into life, before life
On the traces of our African past
Alzheimer’s Disease from the Inside Out
The buddy system behind puberty
A vaccine to stop the most invisible of all viruses
The Gambling Rules of Cell Behavior
A Fireside Chat with Ali Khademhosseini
A Fireside Chat with Anesthesiologist Emery Brown
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