How wonderful would it be if you could deposit your skin cells at a medical facility and get an organ you need within weeks, ready to be transplanted? For decades, scientists have relentlessly worked to recapitulate functionally and physiologically relevant human organs in the lab. Some approaches rely on engineering an unfeasible number of genes in cells or on external cues like growth factors and mechanical signals. But these organs are far from overcoming the barriers of complexity, reproducibility, and time sensitivity, and are thus not ready to be applied in the real world. In today's episode, Dr. Mo Ebrahimkhani, a scientist at Pittsburgh Liver Research Center, discusses how his team used a machine-learning algorithm (called CellNet) to engineer genetic nodes in the stem cells, resulting in the generation of human liver organoids in less than three weeks. Importantly, these organoids were able to capture the complexity of a mature liver. Also learn here how the body map of organs can contribute to the rapid advancement of the field of regenerative medicine. Inspired by Kevin MacLeod is licensed under CC BY 4.0.
A hidden link between amino acid metabolism and peripheral neuropathy in diabetes
The AI model that’s building novel proteins
Countering antibiotic resistance using engineered bacteria
Healing Wounds Faster with the Body’s Own Motion
Fighting Cancer with a Cell-Based Vaccine
A Fireside Chat with Carolyn Bertozzi
Social media: the good, the bad and the hopeful
How preterm infants benefit from emotional connection
Arcade Neuro: brain cells in a dish learn to play Pong with Dr. Brett Kagan
A Fireside Chat with May-Britt Moser
At-home healthcare: monitoring Parkinson’s disease with radio waves
The chronic disease caused by a common virus
A telescope to look into life, before life
On the traces of our African past
Alzheimer’s Disease from the Inside Out
The buddy system behind puberty
A vaccine to stop the most invisible of all viruses
The Gambling Rules of Cell Behavior
A Fireside Chat with Ali Khademhosseini
A Fireside Chat with Anesthesiologist Emery Brown
Join Podbean Ads Marketplace and connect with engaged listeners.
Advertise Today
Create your
podcast in
minutes
It is Free
DNA Today: A Genetics Podcast
Short Wave
Stuff To Blow Your Mind
Unexplainable
پادکست آذرخش مکری - azarakhsh mokri