https://enzymes.bio/ Thus it's attainable that if three prevents collapse of the tetrahedral intermediate, it might do so by perturbing the native setting round this key residue, stopping it from acting as the overall acid. speculate that binding of three to the tetrahedral intermediate is the favored enzyme/substrate complex leading to potent inhibition. Catalytically inactive caspase-6 , apo-caspase-6 and
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