Literally! With Rob Lowe

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4.2K Followers 324 Episodes

This is literally a podcast where people I love, admire, and know well will be in a safe space to really let their hair down (assuming they have any). I will cover the thoughtful to the extremely random. So join me and my guests from the world of movies, TV, sports, music, and culture for fun, wide-ranging, free-wheeling conversations. Subscribe to SiriusXM Podcasts+ to listen to new episodes of Literally with Rob Lowe ad-free. Start a free trial now on Apple Podcasts or by visiting...

Episode List

Chris Pratt: Have Mercy!

Feb 5th, 2026 8:00 AM

Chris Pratt returns to the podcast! Rob’s good friend, golf partner, and “Parks & Rec” co-star Chris Pratt joins the show to discuss his quotable kids, his new movie “Mercy” (featuring a cameo from Chris Pratt’s actual brother), Christmas with Grandpa Arnold Schwarzenegger, Rob’s alien dinner, and much more. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Catherine O'Hara: Booties & Baby Pictures (Re-Release)

Feb 2nd, 2026 8:00 AM

In honor of her passing, we are re-sharing Rob's 2020 conversation with the brilliant actress and comedian Catherine O'Hara.Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Kevin O’Leary: The Shark Is in the Water

Jan 29th, 2026 8:00 AM

Mr. Wonderful himself, Shark Tank’s Kevin O’Leary, joins Rob Lowe to discuss his acting debut alongside Gwyneth Paltrow and Timothée Chalamet in “Marty Supreme,” seventeen years of “Shark Tank,” how to build a watch collection, the future of artificial intelligence, and much more.Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Kevin Jonas: Music That Feels Good

Jan 22nd, 2026 8:00 AM

Kevin and Rob love to talk music, dogs, and fatherhood. Kevin Jonas joins Rob Lowe to discuss his new single, “Changing,” memories of the Jonas Brothers performing at the White House, shooting Christmas movies, their shared love for the song “Torn” by Natalie Imbruglia, and more. Plus, Kevin has questions about “9-1-1: Lone Star” and “Parks & Rec.” Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Julianna Margulies: That's Life in an ER (Re-Release)

Jan 19th, 2026 8:00 AM

This week, we're looking back at Rob's conversation with "The Good Wife" star Julianna Margulies! The two discuss meditating as a family, why she left ER, and Fraterdays! Got a question for Rob? Call our voicemail at (323) 570-4551. Yours could get featured on the show!Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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