Integrative Lyme Solutions with Dr. Karlfeldt

Dr. Geoff Dow – New Clinical Trial for Chronic Babesiosis: Tafenoquine, Malaria Drugs, and Hope for Lyme-Linked Fatigue

Is chronic babesiosis finally getting the scientific attention it deserves?In this episode of Integrative Lyme Solutions, Dr. K sits down with Dr. Geoff Dow, CEO & President of Sixty Degrees Pharmaceuticals, to discuss a groundbreaking clinical trial targeting chronic babesiosis — a common and often overlooked Lyme co-infection. Originally developed for malaria prevention, the drug Tafenoquine (brand name Kodatef®) is now being studied for its potential to treat persistent Babesia infections and Lyme-related fatigue.They explore the science behind red blood cell parasites, how Babesia differs from malaria, why chronic babesiosis remains controversial, and what makes this new trial the first FDA-reviewed IND study focused on chronic disease. If you or a loved one struggle with Lyme-related fatigue, relapsing babesiosis, or limited treatment options, this conversation offers cautious optimism and a closer look at the future of targeted therapies.Key Takeaways:0:00 Introduction3:10 From Malaria Drug Development to Lyme Co-Infections6:45 How Babesia Infects Red Blood Cells and Causes Fatigue10:40 Why Chronic Babesiosis Is Still Controversial14:50 No FDA-Approved Drugs Specifically for Babesiosis18:30 New Clinical Trials for Chronic and Relapsing Babesiosis24:00 Measuring Fatigue as a Primary Endpoint in Chronic DiseaseResources Mentioned:Sixty Degrees Pharmaceuticals - https://www.sixtydegreespharma.comKodatef® (Tafenoquine) Information - Available via company website aboveMount Sinai (Clinical Trial Site) - https://www.mountsinai.orgYale Babesiosis Case Series (Referenced Study) - https://medicine.yale.eduMedical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Dr. Somer DelSignore – Congenital Lyme, Pediatric Neuroinflammation, and the Hidden Root of Autism

Can Lyme disease begin before birth — and could it be driving neurodevelopmental conditions like autism, ADHD, and anxiety?In this episode of Integrative Lyme Solutions, Dr. K is joined by Dr. Somer DelSignore, a leading pediatric integrative clinician, to explore the overlooked science of congenital Lyme and in utero transmission of vector-borne infections. Dr. DelSignore explains how infections such as Borrelia, Bartonella, and Babesia can cross the placenta, disrupt fetal brain development, and silently fuel inflammation that shows up later as behavioral, cognitive, and immune dysfunction.You’ll learn why standard TORCH testing fails to catch these infections, what symptoms parents should watch for in infants and children, and how addressing inflammation, infections, and immune imbalance can dramatically improve outcomes. This episode offers critical insight for parents, practitioners, and anyone focused on true prevention and root-cause healing in pediatric Lyme disease.Key Takeaways:0:00 Introduction and Dr. Somer DelSignore’s clinical journey3:10 From pediatric ICU to integrative Lyme care6:20 Congenital Lyme: 40 years of overlooked science9:00 Why TORCH testing misses vector-borne infections12:45 Preconception testing and prevention strategies15:30 Why treating Lyme before pregnancy matters18:05 Infant symptoms parents should never ignore21:10 Autism, neuroinflammation, and misdiagnosis24:15 The RESET framework for pediatric healing28:10 What real recovery can look like for childrenResources Mentioned:IGeneX Laboratories – https://igenex.comTLABDX (Babesia & Bartonella testing) – https://www.tlabdx.com/Horowitz/MSIDS 38 point symptom checklist – https://projectlyme.org/msids-questionnaire/IV Ozone Therapy – https://health.clevelandclinic.org/ozone-therapySOT (Supportive Oligonucleotide Therapy) – https://projectlyme.org/supportive-oligonucleotide-therapy-sot-for-lyme/Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Dr. Kelly McCann – Lyme, Mold, Mast Cell Activation & Healing the Terrain Through Mind, Body, and Spirit

Why do so many Lyme patients stay sick — even after treating infections, detoxing, and “doing everything right”?In this episode of Integrative Lyme Solutions, Dr. K sits down with functional and environmental medicine pioneer Dr. Kelly McCann to explore why Lyme disease, mold toxicity, and Mast Cell Activation Syndrome (MCAS) are rarely just infections — and why true healing requires addressing the terrain of the body, nervous system, emotions, and spirit. Drawing from her own journey through mold illness and Lyme disease, Dr. McCann explains how immune dysregulation, trauma, limbic system activation, and cell membrane damage keep patients stuck in chronic illness.This conversation dives deep into mast cell activation, mold exposure, Bartonella, phosphatidylcholine therapy, biofilms, nervous system regulation, emotional trauma, spirituality, and why symptoms are not betrayals — but messages. If you’ve been gaslit, dismissed, or feel like your body is working against you, this episode offers validation, insight, and a radically different way to understand Lyme healing.Key Takeaways:0:00 Introduction and Dr. Kelly McCann’s personal healing journey3:00 Mold exposure as a hidden driver of chronic illness6:20 Lyme, Bartonella, and the overlap with mast cell activation9:30 Why siloed medicine fails complex chronic disease patients11:40 Phosphatidylcholine and cell membrane repair explained13:50 When antimicrobial treatment stalls, look beyond infections16:50 Mast cell activation, trauma, and nervous system dysregulation18:40 The limbic system’s role in chronic illness21:10 Emotional trauma, immune boundaries, and people-pleasing24:00 Language, identity, and separating yourself from disease26:10 Terrain theory and why healing requires self-honoring choices29:00 Illness as an invitation, not a punishmentResources Mentioned:Dr. Kelly McCann – https://drkellymccann.comThe Spring Center – https://thespringcenter.comThe Unforgetting Project – https://unforgettingproject.comMicroGen DX (Next Generation Sequencing) – https://microgendx.comByron White Formulas – https://byronwhiteformulas.com _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Dr. Kristi Hellenbrand, DC — Surviving Neuro Lyme: Clinical Diagnosis, the Horowitz Protocol, and Healing When Tests Say “Normal”

What happens when your body is shutting down—but every scan, lab, and specialist says they “can’t find anything”? In this episode, we unpack the reality of Lyme-related neurological illness, the emotional toll of chronic disease, and what it takes to keep moving forward when healing isn’t linear.We’re joined by Dr. Kristi Hellenbrand, DC, chiropractor and author of Let Me Tell You a Secret…She Makes It: a Lyme survival story, who shares how a tick bite in 2020 leads to rapid neurological decline, wheelchair-level symptoms, and relentless migraines—until a clinician treats based on a clinical diagnosis and response to treatment, not just lab confirmation. Kristi walks us through the decision points that change everything: antibiotics as an early signal, later testing that reveals a viral layer, and a pivotal turn to the Horowitz protocol (including double-dose dapsone) as part of her path back to remission.Key Takeaways:03:45 Lyme can first appear as heart and neurological symptoms—not joint pain.07:15 Clinical diagnosis can move treatment forward when labs and specialists stall.10:30 Response to treatment can confirm infection before tests do.13:10 Healing from Lyme is nonlinear and follows the grief cycle.14:25 The Horowitz protocol helped resolve daily, debilitating migraines.19:15 Retracing symptoms signal healing in reverse order—not relapse.31:00 Fear is inflammatory; regulating the nervous system supports long-term recovery.Resources Mentioned:Let Me Tell You a Secret...She Makes It.: - a Lyme survival story - https://www.amazon.com/Let-Tell-You-Secret-Makes/dp/B0CJB825R1Lyme Lives Here - https://www.lymeliveshere.com/#lymewarrior #chronicillness #TheKarlfeldtCenter #IntegrativeLymeSolutionsWant to guest on our shows?Calendly Link for Integrative Lyme Solutions: https://calendly.com/drmichaelk/integrative-lyme-solutions-podcast-interviewCalendly Link for Integrative Cancer Solutions: https://calendly.com/drmichaelk/podcast-interviewCalendly Link for Dr. K Show: https://calendly.com/drmichaelk/dr-k-show-interviewBreaking Free From Lyme: A Comprehensive Guide to Healing and Recovery-URL: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lyme-Price: $24.99-Discount Code: LYMEPODCASTUnleashing 10X Power: A Revolutionary Approach to Conquering Cancer-URL: https://store.thekarlfeldtcenter.com/products/unleashing-10x-power-Price: $24.99-Discount Code: CANCERPODCAST1Healing Within: Unraveling the Emotional Roots of Cancer-URL: https://store.thekarlfeldtcenter.com/products/healing-within-Price: $24.99-Discount Code: CANCERPODCAST2The Science and Spirit of Transformation: A Holistic Guide to Elevating Health, Consciousness, and Purpose-URL: https://store.thekarlfeldtcenter.com/products/the-science-and-spirit-of-transformation-Price: $24.99-Discount Code: DRKSHOWPODCAST _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!

Cracking the Chronic Illness Code with Dr. Eric Gordon: Lyme, Mold, Mast Cells, and the Future of AI-Guided Healing

Dr. Eric Gordon—Medical Director at Gordon Medical Associates and President of the Gordon Medical Research Center—joins Dr. Karlfeldt for a wide-ranging conversation on what it really takes to help “end-of-the-line” patients with complex, chronic illness. With 45+ years of clinical experience and deep involvement in research on ME/CFS, Lyme disease, and autoimmune conditions, Dr. Gordon offers a grounded, clinician-to-clinician look at why so many patients remain undiagnosed, misunderstood, or stuck despite seeing multiple providers.In this episode, you’ll learn why chronic illness is rarely “in the book,” and why recovery often requires detective work across toxin load, infectious burden, genetics, immune dysfunction, and environmental triggers. Dr. Gordon breaks down how modern medicine’s siloed specialties can miss multi-system patterns—and why tools like advanced testing and AI may become essential to sift exploding research (like microbiome discoveries) into something clinically useful. They also explore the evolving landscape of long COVID research, the importance of identifying patient subtypes (instead of lumping everyone into one diagnosis), and what this shift could mean for faster, more affordable healing.If you’ve tried the “usual” protocols and still don’t improve, this conversation reframes the journey: why complexity doesn’t mean hopelessness—and how the next wave of systems biology, smarter data-mining, and targeted interventions may finally change the game for chronic fatigue, Lyme, mold illness, and beyond.Key Topics CoveredWhy “complex chronic illness” usually isn’t a simple diagnosis—and why that matters for treatmentThe “end-of-the-line” patient: what it means when you’ve already seen many good doctorsHow toxin load, infections, genetics, and terrain combine into a personalized illness patternWhy medical silos and protocol-based care often fail complex patientsMold exposure and mycotoxin sensitivity: why environment can block progressMast cell activation and reactivity: why treatment tolerance can be a major barrierThe microbiome information explosion—and why AI is becoming necessary to interpret itGarbage-in/garbage-out in AI: why context and quality data still matterLong COVID as a turning point: validating post-viral illness and advancing immune researchThe importance of subtyping ME/CFS, long COVID, and Lyme presentations to find what actually works _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K’s Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!