Sex-Dependent Responses to Cannabinoids with Ziva Cooper, MD

2022-11-23

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Dr. Ziva Cooper is the Director of the UCLA Center for Cannabis and Cannabinoids. She is also an Associate Professor in the Department of Psychiatry and Biobehavioral Sciences and Department of Anesthesiology at the David Geffen School of Medicine. Her current research involves understanding variables that influence both the therapeutic potential and adverse effects of cannabis and cannabinoids through double-blind, placebo-controlled studies. One of the variables Ziva and her team are studying is the differences between ...

Her current research involves understanding variables that influence both the therapeutic potential and adverse effects of cannabis and cannabinoids through double-blind, placebo-controlled studies.

One of the variables Ziva and her team are studying is the differences between men and women in their response to the abuse-related and pain-relieving effects of cannabinoids, and the role that circulating hormones and endocannabinoids contribute to these differences,

We discuss:

Key differences in how cannabis affects males vs. females
Females metabolize THC differently than males
Cannabis use tolerance differences in males vs. females
Female reproductive hormones play a role in sensitivity to THC
The importance of placebo-controlled studies
Male vs. Female differences in self-reporting pain, side effects, etc.

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