Magdalena Götz: Direct Conversion of Astrocytes Into Neurons – Progress and Therapeutic Potential
Brain Ponderings podcast with Mark Mattson

Magdalena Götz: Direct Conversion of Astrocytes Into Neurons – Progress and Therapeutic Potential

2025-02-04
Someday it may be possible to restore neuronal networks that have been lost or damaged by brain injury or in neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases. There are as many astrocytes in the human brain as there are neurons and the astrocytes generally do not die in brain injuries and neurodegenerative disorders. Professor Magdalena Götz has shown that astrocytes can be converted directly into neurons using molecular biology technologies to manipulate a few transcription factors that...
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