361 | Bonnie Bassler on How Bacteria Talk and Work Together

One of the characteristics of life is that living organisms gather information and put it to use. Even one of the simplest lifeforms, bacteria, are able to sense features of their surroundings and alter their behavior accordingly. Most impressively, they are able to sense the presence of similar bacteria by a process called quorum sensing. Today's guest, Bonnie Bassler, is a leader in this field, and explains how quorum sensing allows groups of bacteria to do things (including in our bodies) that wouldn't be possible for individual bacteria.

Blog post with transcript: https://preposterousuniverse.com/podcast/2026/07/20/361-bonnie-bassler-on-how-bacteria-talk-and-work-together/

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Bonnie Bassler received a Ph.D. in biochemistry from Johns Hopkins University. She is currently Andrew K. Golden University Professor of Molecular Biology at Princeton University and a Howard Hughes Medical Institute Investigator. She is a member of the National Academy of Sciences, National Academy of Medicine, and the American Academy of Arts and Sciences. Among her awards are a MacArthur Fellowship, the Gruber Prize in Genetics, and the National Medal of Science.

• Lab web site
• Princeton web page
• Google Scholar publications
• Wikipedia