It’s the Manchester derby, with City hosting United at the Etihad Stadium. United will be hoping to better their 3-0 defeat in the reverse fixture.
Elsewhere, Oliver Glasner’s Crystal Palace travel to the Tottenham Hotspur Stadium to take on Spurs, Newcastle host in-form Wolves, while Everton welcome West Ham to Goodison Park.
Host: Michael Bailey
Guests: Tim Spiers, Jon Mackenzie, Joey D'Urso
Producer: Mike Stavrou
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Has Emery made Aston Villa title contenders?
Weekend Preview: Can Arsenal end Villa's streak?
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Is Kompany’s iconic status buying him more time?
Jorginho interview: Arteta's plan, 'unbelievable' Havertz & penalties
Can a rebooted Trent lead Liverpool to the title?
Weekend Preview: Will Angeball bounce back at Man City?
Is Onana really to blame?
Will Ancelotti leave Real Madrid for Brazil?
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Weekend Preview: Liverpool head to Man City as top two clash
Lyon and the danger of multi-club ownership
Inter Milan: Winning titles, losing money
Barcelona 'bet the house' on their future - will it work?
What Everton’s punishment could mean for Man City & Chelsea
Premier League roundtable: The season so far
Man United’s leadership limbo: Arnold’s departure explained
Napoli: From champions to chaos in six months
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