Links:
About This Episode:
Alzheimer’s disease has a profound impact on individuals, families, and societies worldwide. As a progressive neurodegenerative disease, it not only robs individuals of their cognitive abilities but also places an immense emotional and economic burden on caregivers.
Mechanistically, the causes of Alzheimer’s are incredibly complex and not fully understood. And in terms of treatment, the landscape appears challenging. Drug discovery efforts for dementias, including Alzheimer’s, have faced setbacks, leaving a void in effective treatments. Consequently, attention has shifted toward preventive strategies, including dietary patterns.
From a prevention standpoint, both genetics and lifestyle should be considered. Which throws up many interesting questions…
To what extent do genetic factors contribute to Alzheimer’s risk compared to lifestyle choices, and how does this interaction influence disease development?
What role does lifestyle play in Alzheimer’s risk, and is there evidence supporting the influence of specific nutrients on cognitive health?
How do diet patterns impact Alzheimer’s risk? Are there discernible risk differences associated with specific dietary choices, and how do these interact with genetic factors, such as the ApoE genotype?
In this episode, Drs. Ayesha Sherzai and Dean Sherzai are on the podcast to answer these questions and discuss this topic in more depth.
About The Guests:
Dr. Ayesha Sherzai is a neurologist and co-director of the Alzheimer’s Prevention Program at Loma Linda University, where she leads the Lifestyle Program for the Prevention of Neurological Diseases. She completed a dual training in Preventative Medicine and Neurology at Loma Linda University, and a fellowship in Vascular Neurology and Epidemiology at Columbia University. She is also a trained plant-based culinary artist.
Dr. Dean Sherzai is co-director of the Alzheimer’s Prevention Program at Loma Linda University. Dean trained in Neurology at Georgetown University School of Medicine, and completed fellowships in neurodegenerative diseases and dementia at the National Institutes of Health and UC San Diego. He also holds a PhD in Healthcare Leadership with a focus on community health from Andrews University.
#408: Mario Kratz, PhD – Is Eating Full-fat Dairy, Low-fat Dairy, or No Dairy Better for Cardiometabolic Health?
#407: Polyphenols - Impact on Blood Pressure, Endothelial Function & Heart Disease Risk
#406: Polyphenols & Cognitive Health
#405: Adrian Brown, PhD - Dietary Strategies in Type 2 Diabetes
#404: Prof. Marion Hetherington – Psychology and Development of Food Preference & Eating Behaviour
#403 Prof. David Jacobs – Food Synergy & The Top-Down Approach to Nutrition Research
#402: Prof. Leanne Redman – Pregnancy, Maternal Diet & Intergenerational Transmission of Obesity
#401: Quack Asylum – Part 2: Greger, Berg & Saladino
#400: Quack Asylum – Part 1: Malhotra & DiNicolantonio
#399: Prof. James Betts – Does Fasting Have Benefits Beyond Those Caused By Calorie Restriction?
#398: Carole Hooven, PhD – Testosterone: Behavioural Endocrinology & Sex Differences
#397: Dietary Nitrates & Nitrites
#396: Leigh Frame, PhD – Nutrient Trials: RCT Design, Ethics and Placebo Groups
#395: Prof. Carel le Roux – Current Thinking in Obesity Treatment
#394: Gar Benn – Nutrition Coaching Q&A
#393: Vitamin D: Does Supplementation Actually Improve Health?
#392: Clare Pettinger, PhD, RD – Environmentally Sustainable Diets & Food Access
#391: Is There a Body Weight Set Point?: Models of Body Mass Regulation
#390: Gil Carvalho MD, PhD – Dairy, Olive Oil & Diet Debates: Understanding Evidence
#389: Renee McGregor, RD – Why Are Athletes Under-Eating?
Create your
podcast in
minutes
It is Free
Practically Healthy by Dr. Melina
ZOE Science & Nutrition
Intermittent Fasting Stories
The Model Health Show
Nutrition Diva