GLPs: Myths, Microdosing, Studies and Cautions with McCall McPherson

Episode Highlights with McCall McPherson

• How GLPs were developed and how they became popular for weight loss
• What GLPs actually are and how they work 
• The inflammatory pieces related to GLP use and her theory that they may reduce inflammation
• Inflammation is a common factor in chronic disease but tough to pinpoint and affect, though easy to test
• She measures HS-CRP on labs to check inflammation 
• How she is seeing a consistent reduction in autoimmune antibodies with GLPs
• What to know about muscle loss with GLPs and how to maintain muscle mass if you take them: eat enough protein and strength-building activity 
• Heart disease kills more people than all cancers combined 
• A couple of important studies looking at cardiovascular death risk for diabetics on GLPs - 51% risk reduction with GLP use
• The select trial in non-diabetics found a 21% reduction in heart attack and stroke risk with GLPs
• How being undernourished and underhydrated can impact metrics like HRV and resting heart rate if people don’t drink enough water on this
• The real data about thyroid risk and why this is really important to understand 
• Dosing is so important and overdosing is responsible for the majority of issues

Resources Mentioned

• Modern Weight Loss’s: GLP-1’s Decoded Guide 
• McCall McPherson's website