#136 | Live Long Strong; Dodge the #1 Killer (CVD) | Michael Twyman MD

2024-06-09

Pro Level Supplements for WiseAthletes The USA declared war on heart disease in 1955. 70 years later it is still the leading cause of death. What about statins and all that medical progress we’ve had. Exactly, what about it? Dr Michael Twyman is a board certified cardiologist who runs Apollo Cardiology, a clinic serving patients from all over the world. His approach is to understand cardiovascular health from a whole body perspective. Rather than focus on LDL and HDL and apoB, he says we need to look at the bigger p...

Pro Level Supplements for WiseAthletes

The USA declared war on heart disease in 1955. 70 years later it is still the leading cause of death. What about statins and all that medical progress we’ve had. Exactly, what about it?

Dr Michael Twyman is a board certified cardiologist who runs Apollo Cardiology, a clinic serving patients from all over the world. His approach is to understand cardiovascular health from a whole body perspective. Rather than focus on LDL and HDL and apoB, he says we need to look at the bigger picture of cardiovascular health….namely cardiovascular health as a marker of whole body health. He says plaques can start building early in life....stop the progression now to eliminate the need for dramatic interventions with significant side effect later in life.

We discuss specific behaviors and supplements and even medications to signal the body to stop building plaques. A statin is only one of many potential solutions. Since recording this episode, I have stopped taking my low-dose statin that was significantly reducing my muscle power, and replaced it with better tools.

Stop damaging the Glycocalyx (the protective barrier to the lining of arteries)
Stop making so many ApoB particles
Make more receptors to remove more ApoB particles
Lower reabsorption and absorption of cholesterol from food in gut

Bullet points

Damage to glycocalx
- Causes: high oxidative stress (mitochondrial disfunction), inflammation from any source: gut related, infection (COVID), smoking, high insulin, high glucose
- Signs: high BP, erectile dysfunction
Supplements to consider
- Vit k2 - keep calcium in bone not arteries
- Garlic - support glyocalix health
- Berberine — increase LDL receptors (like a weak pcsk9)
- Bergomot - lower LDL production (like a weak statin)
- Ezetimibe (not supplement) — reabsorption of cholesterol
- Aspirin (81 mg) - complicated. Had an event? Aspirin for life. No event yet? Higher CAC? Aspirin. Unless high risk of bleeding.
Blood markers review
- Homocysteine