Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

2025-12-11

Download

In this Huberman Lab Essentials episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University. We discuss how microbes in our gut impact our mental and physical health and how diet and the environment affect the gut microbiome. We explain how lifestyle factors such as antibiotics and Western-style diets (high fat, low fiber and rich in processed foods) can damage gut diversity and whether prebiotics or probiotics are useful tools. Throughout the episode, we highlight evidence-based dietary and...

In this Huberman Lab Essentials episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University.

We discuss how microbes in our gut impact our mental and physical health and how diet and the environment affect the gut microbiome. We explain how lifestyle factors such as antibiotics and Western-style diets (high fat, low fiber and rich in processed foods) can damage gut diversity and whether prebiotics or probiotics are useful tools. Throughout the episode, we highlight evidence-based dietary and lifestyle strategies for improving gut health.

Episode show notes: https://go.hubermanlab.com/VXfckJf

Thank you to our sponsors

AG1: https://drinkag1.com/huberman

Joovv: https://joovv.com/huberman

Function: https://functionhealth.com/huberman

Timestamps

00:00:00 Justin Sonnenburg

00:00:20 What is the Microbiome?

00:02:55 Microbiome Origin, Babies, Environmental Factors

00:04:47 Healthy Microbiome, Individuality; Industrialized vs Traditional Populations

00:07:06 Sponsor: AG1

00:08:30 “Reprogramming” the Gut Microbiome; Antibiotics, Western Diet