Lege Sjur Even Aunmo er opptatt av å følge med på forskning. I denne episoden forteller han om problemene med å leve av planter. Planter har nemlig forsvarsmekanismer mot å bli spist. De kan dessuten stjele mineraler, trigge immunsystemet, tilføre tungmetall og gi næring til kreft. Selv foretrekker han et kosthold bestående utelukkende av animalske produkter. Han synes det er beklagelig at rådene har blitt politiske gjennom at de har tatt inn klimasaken, fremfor at de er en mest mulig sann fremstilling av hva ulik...
Lege Sjur Even Aunmo er opptatt av å følge med på forskning. I denne episoden forteller han om problemene med å leve av planter. Planter har nemlig forsvarsmekanismer mot å bli spist. De kan dessuten stjele mineraler, trigge immunsystemet, tilføre tungmetall og gi næring til kreft. Selv foretrekker han et kosthold bestående utelukkende av animalske produkter. Han synes det er beklagelig at rådene har blitt politiske gjennom at de har tatt inn klimasaken, fremfor at de er en mest mulig sann fremstilling av hva ulike typer mat gjør med kroppen. Aunmo legger frem forskningsevidens som peker i motsatt retning av kostholdsrådene norske myndigheter har lagt frem nylig. Han har mange suksesshistorier fra pasienter med autoimmune sykdommer, diabetes og andre sykdommer, som har blitt friske etter at de sluttet å spise bestemte typer planter, produkter fra planter eller utelukket dem helt fra kosten.
Sjur Even Aunmo:
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Grønnsaker uten noen kjent form for gluten:
• hodekål, blomkål, brokkoli, paprika, rødbeter, bladbete, squash, potet, søtpotet, gulrøtter, gresskar, romano-salat, indisk bladsennep, spinat, grønnkål
• Obs: Selv om disse plantene ikke inneholder gluten, finnes det andre stoffer i dem som er uheldige. Paprika, for eksempel, hører til søtvier-familien, sammen med potet og tobakk. De forsvarer seg mot mennesker, dyr og insekter med lektiner og solanin. Spinat inneholder mye oksalat som stjeler kalsium fra kroppen. Det finnes igjen i nyrestener og mistenkes for å stimulere brystkreft. Grønnsaker inneholder druesukker, som er et viktig næringsstoff for kreft. Grønnsaker som vokser over bakken inneholder ofte mindre sukker enn de som vokser under bakken. De minst usunne grønnsakene på listen synes å være hodekål, blomkål og brokkoli, på tross av at disse danner goitrin, et stoff som motvirker dannelsen av stoffskiftehormon.
Diverse kilder:
• Mindre kjøtt, mer plantebasert: Her kommer De nordiske ernæringsanbefalingene 2023
• Helsedirektoratets kostråd
• The Seven Countries Study (søk)
• Paleo diet (søk)
• Keto diet (søk)
• Carnivore diet (søk)
› Relaterte AJP-episoder:
• AJP 61 | Sjur Even Aunmo – Fikk sparken for å snakke om bivirkninger
Relatert forskning:
› FETT
› https://doi.org/10.1136/bmj.e8707 Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis
› https://doi.org/10.1136/bmj.i1246 Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)
› https://doi.org/10.3945/ajcn.2009.27725 Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease
› https://doi.org/10.1186/s12937-017-0254-5 The effect of replacing saturated fat with mostly n-6 polyunsaturated fat on coronary heart disease: a meta-analysis of randomised controlled trials
› https://doi.org/10.1016/j.jacc.2020.05.077 Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations: JACC State-of-the-Art Review
› http://dx.doi.org/10.1136/openhrt-2014-000196 Evidence from randomised controlled trials did not support the introduction of dietary fat guidelines in 1977 and 1983: a systematic review and meta-analysis
› http://dx.doi.org/10.1136/bmjebm-2019-111180 Fat or fiction: the diet-heart hypothesis
› https://www.mn.uio.no/ibv/tjenester/kunnskap/plantefys/leksikon/h/herdet-fett.html
› https://doi.org/10.1046/j.1471-4159.1997.68052092.x 4-Hydroxynonenal-Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease
› https://doi.org/10.1016/j.freeradbiomed.2006.07.021 Induction of mitochondrial nitrative damage and cardiac dysfunction by chronic provision of dietary ω-6 polyunsaturated fatty acids
› https://doi.org/10.1038/s41467-018-05614-6 Dietary stearic acid regulates mitochondria in vivo in humans
› http://dx.doi.org/10.17140/AFTNSOJ-1-123 Oxidation of Polyunsaturated Fatty Acids and its Impact on Food Quality and Human Health
› https://doi.org/10.1194/jlr.M026179 Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells
› https://doi.org/10.1021/jf049207s Effect of the Type of Frying Culinary Fat on Volatile Compounds Isolated in Fried Pork Loin Chops by Using SPME-GC-MS
› STATINER (KOLESTEROLSENKENDE STOFFER)
› http://dx.doi.org/10.1136/bmjopen-2018-023085 Statins for the primary prevention of cardiovascular disease: an overview of systematic reviews
› http://dx.doi.org/10.1136/bmjopen-2014-007118 The effect of statins on average survival in randomised trials, an analysis of end point postponement
› https://doi.org/10.1001/archinternmed.2010.182 Statins and All-Cause Mortality in High-Risk Primary Prevention: A Meta-analysis of 11 Randomized Controlled Trials Involving 65 229 Participants
› https://www.felleskatalogen.no/medisin/lipitor-upjohn-eesv-pfizer-560999
› https://www.felleskatalogen.no/medisin/zocor-organon-565655
› https://www.legemiddelhandboka.no/L8.15.1/Statiner
› https://www.bmj.com/campaign/statins-open-data Statins - a call for transparent data
› https://doi.org/10.1001/archinternmed.2011.625 Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Women's Health Initiative
› https://doi.org/10.1007/s40264-017-0620-4 Amyotrophic Lateral Sclerosis Associated with Statin Use: A Disproportionality Analysis of the FDA’s Adverse Event Reporting System
› https://doi.org/10.1001/jamainternmed.2020.6084 Evaluation of Time to Benefit of Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years
› https://doi.org/10.1016/j.atherosclerosis.2022.07.003 Statin therapy for the primary prevention of cardiovascular disease: Cons
› http://doi.org/10.1161/STROKEAHA.121.034576 Lipid-Lowering Therapy and Hemorrhagic Stroke RiskLipid-Lowering Therapy and Hemorrhagic Stroke Risk
› KJØTT
› https://www.acpjournals.org/doi/full/10.7326/M19-0622 Effect of Lower Versus Higher Red Meat Intake on Cardiometabolic and Cancer Outcomes A Systematic Review of Randomized Trials
› https://doi.org/10.3945/ajcn.116.142521 Total red meat intake of ≥0.5 servings/d does not negatively influence cardiovascular disease risk factors: a systemically searched meta-analysis of randomized controlled trials
› https://doi.org/10.3945/ajcn.113.062638 Meat intake and cause-specific mortality: a pooled analysis of Asian prospective cohort studies
› FISK
› https://doi.org/10.1093/jn/nxab112 Biomarkers and Fatty Fish Intake: A Randomized Controlled Trial in Norwegian Preschool Children
› https://doi.org/10.1007/s12016-013-8363-1 Fish Allergy: In Review
› KOLESTEROL
› http://dx.doi.org/10.1136/bmjopen-2015-010401 Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review
› https://doi.org/10.1016/j.mehy.2018.09.019 Inborn coagulation factors are more important cardiovascular risk factors than high LDL-cholesterol in familial hypercholesterolemia
› PMID: 18277343 ApoB/ApoA1 ratio and subclinical atherosclerosis
› https://doi.org/10.1016/0021-9150(89)90130-5 Cigarette smoking renders LDL susceptible to peroxidative modification and enhanced metabolism by macrophages
› https://doi.org/10.1161/01.CIR.93.7.1346 Cigarette Smoking Potentiates Endothelial Dysfunction of Forearm Resistance Vessels in Patients With Hypercholesterolemia: Role of Oxidized LDL
› https://doi.org/10.1161/01.CIR.97.20.2012 Passive Smoking Induces Atherogenic Changes in Low-Density Lipoprotein
› https://doi.org/10.1016/j.atherosclerosis.2008.04.046 Smoking and smoking cessation—The relationship between cardiovascular disease and lipoprotein metabolism: A review
› https://doi.org/10.1161/ATVBAHA.113.300156 Smoking and Cardiovascular Disease
› https://doi.org/10.3402/fnr.v59.29240 LDL biochemical modifications: a link between atherosclerosis and aging
› https://doi.org/10.1016/j.cjca.2017.07.015 Association Between Circulating Oxidized LDL and Atherosclerotic Cardiovascular Disease: A Meta-analysis of Observational Studies
› https://doi.org/10.1054/plef.2000.0204 Why is glycated LDL more sensitive to oxidation than native LDL? A comparative study.
› KARBOHYDRAT
› https://www.helsedirektoratet.no/rapporter/anbefalinger-om-kosthold-ernaering-og-fysisk-aktivitet/Anbefalinger%20om%20kosthold%20ern%C3%A6ring%20og%20fysisk%20aktivitet.pdf/_/attachment/inline/2f5d80b2-e0f7-4071-a2e5-3b080f99d37d:2aed64b5b986acd14764b3aa7fba3f3c48547d2d/Anbefalinger%20om%20kosthold%20ern%C3%A6ring%20og%20fysisk%20aktivitet.pdf
› FRUKTOSE
› https://doi.org/10.1016/j.jhep.2021.02.027 Fructose- and sucrose- but not glucose-sweetened beverages promote hepatic de novo lipogenesis: A randomized controlled trial
› https://doi.org/10.1093/ajcn/nqaa332 Effects of fructose restriction on liver steatosis (FRUITLESS); a double-blind randomized controlled trial
› https://doi.org/10.5223/pghn.2021.24.5.483 The Relationship between Daily Fructose Consumption and Oxidized Low-Density Lipoprotein and Low-Density Lipoprotein Particle Size in Children with Obesity
› KUNSTIG SØTNING
› https://doi.org/10.1016/s0378-8741(99)00081-1 Effects of chronic administration of Stevia rebaudiana on fertility in rats
› https://doi.org/10.1371/journal.pone.0000698 Intense Sweetness Surpasses Cocaine Reward
› https://doi.org/10.1016/j.cell.2022.07.016 Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance
› https://doi.org/10.1289/ehp.8711 First Experimental Demonstration of the Multipotential Carcinogenic Effects of Aspartame Administered in the Feed to Sprague-Dawley Rats
› https://doi.org/10.1289/ehp.10271 Life-Span Exposure to Low Doses of Aspartame Beginning during Prenatal Life Increases Cancer Effects in Rats
› DIABETES
› https://doi.org/10.1001/jama.295.6.655 Low-Fat Dietary Pattern and Risk of Cardiovascular DiseaseThe Women's Health Initiative Randomized Controlled Dietary Modification Trial – se side 661, økt hjerte/kar-risk sfa. Lavfett-diett
› https://doi.org/10.3945/ajcn.110.010843 Effects of a low-fat dietary intervention on glucose, insulin, and insulin resistance in the Women’s Health Initiative (WHI) Dietary Modification trial
› https://doi.org/10.1007/s11745-008-3274-2 AOCS Lipids (lavranket journal) Carbohydrate Restriction has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet
› https://doi.org/10.1161/ATVBAHA.114.303284 Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease- ArtThromVas prospektiv kohort
› https://doi.org/10.1097/MOL.0b013e328306a057 Glycation as an atherogenic modification of LDL : Current Opinion in Lipidology
› https://doi.org/10.1016/0021-9150(93)90084-8 Glycosylated low density lipoprotein is more sensitive to oxidation: implications for the diabetic patient?
› https://doi.org/10.2337/diabetes.55.02.06.db05-1103 Loss of Endothelial Glycocalyx During Acute Hyperglycemia Coincides With Endothelial Dysfunction and Coagulation Activation In Vivo
› https://doi.org/10.1016/S0895-7061(00)01260-7 Blood viscosity and blood pressure: role of temperature and hyperglycemia
› https://doi.org/10.2337/dc13-1374 Blood Viscosity in Subjects With Normoglycemia and Prediabetes
› https://doi.org/10.1007/s00592-017-1004-z Elevated 1-h post-challenge plasma glucose levels in subjects with normal glucose tolerance or impaired glucose tolerance are associated with whole blood viscosity
› https://doi.org/10.1080/09674845.2010.11730293 Blood viscosity at different stages of diabetes pathogenesis.
› DIABETES-DEMENS
› https://doi.org/10.1212/WNL.53.9.1937 Diabetes mellitus and the risk of dementia - The Rotterdam Study
› https://doi.org/10.1016/S1474-4422(05)70284-2 Lancet Neurology 2006, sysrew lavere evidensgrad. Risk of dementia in diabetes mellitus: a systematic review
› https://doi.org/10.1111/j.1445-5994.2012.02758.x Diabetes as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies
› https://doi.org/10.1016/j.arr.2019.100944 Diabetes mellitus and risks of cognitive impairment and dementia: A systematic review and meta-analysis of 144 prospective studies
› https://doi.org/10.1177/193229680800200619 Alzheimer's Disease is Type 3 Diabetes—Evidence Reviewed
› https://doi.org/10.3390/ijerph120708281 Evaluating the Association between Diabetes, Cognitive Decline and Dementia
› https://doi.org/10.3390/ijms21030934 Ketone Bodies Promote Amyloid-β1–40 Clearance in a Human in Vitro Blood–Brain Barrier Model
› https://doi.org/10.1038/s41574-018-0048-7 Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications
› https://doi.org/10.1038/s41586-020-2247-3 APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline
› DIABETES NYRESYKDOM
› https://doi.org/10.2337/diacare.27.2007.S79 Nephropathy-in-Diabetes Nephropathy in Diabetes
› Diabetic Nephropathy: Diagnosis, Prevention, and Treatment
› https://doi.org/10.1016/S0272-6386(96)90538-7 Diabetic nephropathy in type II diabetes
› DIABETES ØYESYKDOM
› https://doi.org/10.1016/S0140-6736(09)62124-3 Diabetic retinopathy
› https://doi.org/10.1016/S2213-8587(18)30128-1 Incidence and progression of diabetic retinopathy: a systematic review
› DIABETES HJERTE- OG KAR-SYKDOM
› https://doi.org/10.1001/jamacardio.2020.7073 Association of Lipid, Inflammatory, and Metabolic Biomarkers With Age at Onset for Incident Coronary Heart Disease in Women
› PLANTE-ANTINÆRINGSSTOFF, VERN OG GIFT
› https://doi.org/10.1016/j.foodchem.2008.01.056 Food Chemistry 2008 Bioaccessibility of Ca, Mg, Mn and Cu from whole grain tea-biscuits: Impact of proteins, phytic acid and polyphenols
› https://doi.org/10.1002/mnfr.200900099 Phytate in foods and significance for humans: food sources, intake, processing, bioavailability, protective role and analysis.
› https://doi.org/10.1046/j.1440-6047.1999.00038.x Oxalate content of foods and its effect on humans
› https://doi.org/10.1104/pp.109.2.347 Lectins as plant defense proteins.
› https://doi.org/10.1016/j.taap.2009.03.012 Effects of wheat germ agglutinin on human gastrointestinal epithelium: Insights from an experimental model of immune/epithelial cell interaction
› https://doi.org/10.1038/s41531-018-0066-0 Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat
› https://doi.org/10.1016/S0140-6736(05)79894-9 Identification of intact peanut lectin in peripheral venous blood
› https://doi.org/10.1136/bmj.318.7190.1023 Do dietary lectins cause disease?
› https://doi.org/10.1016/S0015-0282(16)54596-8 Lectin binding of endometrium in women with unexplained infertility
› https://doi.org/10.1016/S0271-5317(88)80133-7 Changes in organs and tissues induced by feeding of purified kidney bean (Phaseolus vulgaris) lectins
› https://doi.org/10.3390/molecules20022014 Insecticidal Activity of Plant Lectins and Potential Application in Crop Protection
› https://doi.org/10.1210/endo-113-6-1921 Bound Lectins that Mimic Insulin Produce Persistent Insulin-Like Activities
› https://doi.org/10.1042/BJ20071137 Contribution of leptin receptor N-linked glycans to leptin binding
› https://doi.org/10.1111/j.1365-2249.2007.03368.x Potato lectin activates basophils and mast cells of atopic subjects by its interaction with core chitobiose of cell-bound non-specific immunoglobulin E
› https://doi.org/10.1002/(SICI)1521-4141(199903)29:03 Dietary lectins can induce in vitro release of IL-4 and IL-13 from human basophils
› https://doi.org/10.1016/j.ekir.2018.07.020 Secondary Oxalate Nephropathy: A Systematic Review
› http://dx.doi.org/10.1136/gut.16.3.193 The effect of tea on iron absorption.
› PMID: 1862 Disler PB, Lynch SR, Torrance JD, et al. The mechanism of the inhibition of iron absorption by tea. The South African Journal of Medical Sciences. 1975 ;40(4):109-116.
› https://doi.org/10.1016/0887-2333(95)00113-1 Effects of saponins and glycoalkaloids on the permeability and viability of mammalian intestinal cells and on the integrity of tissue preparationsin vitro
› https://doi.org/10.1079/BJN2002725 The biological action of saponins in animal systems: a review
› http://doi.org/10.1093/carcin/bgp082 Lung tumor promotion by curcumin
› https://doi.org/10.3945/ajcn.2009.26736M Cancer incidence in vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford)
› https://doi.org/10.3382/ps.0550716 Antithyroid Activity of Goitrin in Chicks
› https://doi.org/10.1016/s0278-6915(82)80294-9 Hepatic effects of R-goitrin in in Sprague-Dawley rats
› https://doi.org/10.1002/ana.24448 Vagotomy and subsequent risk of Parkinson's disease --> https://doi.org/10.1038/s41531-018-0066-0
› Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat
› http://doi.org/10.1056/NEJMra2010852 Salicylate Toxicity
› https://doi.org/10.1021/jf0113070 Relationship between Cyanogenic Compounds in Kernels, Leaves, and Roots of Sweet and Bitter Kernelled Almonds
› https://doi.org/10.1179/146532810X12637745451951Cyanide poisoning caused by ingestion of apricot seeds
› https://doi.org/10.3390/toxins11060324 Ricin: An Ancient Story for a Timeless Plant Toxin
› https://doi.org/10.1016/j.taap.2009.03.012Effects of wheat germ agglutinin on human gastrointestinal epithelium: Insights from an experimental model of immune/epithelial cell interaction
› GLUTEN
› https://doi.org/10.1080/00365520500235334 Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines
› https://doi.org/10.1053/j.gastro.2008.03.023 Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3
› https://doi.org/10.1016/j.jprot.2017.03.026 A curated gluten protein sequence database to support development of proteomics methods for determination of gluten in gluten-free foods
› https://doi.org/10.1111/jgh.13703 What is gluten?
› https://doi.org/10.1186/s41043-015-0032-y The opioid effects of gluten exorphins: asymptomatic celiac disease
› https://doi.org/10.1016/j.peptides.2015.07.013 Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects
› SOYA
› https://doi.org/10.1271/bbb.70516Soymorphins, novel μ opioid peptides derived from soy β-conglycinin β-subunit, have anxiolytic activities.
› TILSETNINGSSTOFFER
› https://doi.org/10.3233/NHA-170023 A randomized trial of the effects of the no-carrageenan diet on ulcerative colitis disease activity
› https://doi.org/10.1053/j.gastro.2021.11.006 Randomized Controlled-Feeding Study of Dietary Emulsifier Carboxymethylcellulose Reveals Detrimental Impacts on the Gut Microbiota and Metabolome
› https://doi.org/10.1002/ijc.21925 Processed meat consumption, dietary nitrosamines and stomach cancer risk in a cohort of Swedish women
› KETOGENISITET/KREFT
› https://oslo-universitetssykehus.no/behandlinger/pet-undersokelse
› https://stanfordhealthcare.org/medical-tests/p/pet-scan/what-to-expect.html
› https://www.sciencedirect.com/topics/medicine-and-dentistry/warburg-effect
› https://doi.org/10.1016/j.tibs.2015.12.001 The Warburg Effect: How Does it Benefit Cancer Cells?
› https://doi.org/10.1080/01635581.2019.1650942 Feasibility, Safety, and Beneficial Effects of MCT-Based Ketogenic Diet for Breast Cancer Treatment: A Randomized Controlled Trial Study
› https://doi.org/10.1093/jnci/djs399 Dietary Glycemic Load and Cancer Recurrence and Survival in Patients with Stage III Colon Cancer: Findings From CALGB 89803
› https://doi.org/10.18632/aging.101382 Ketogenic diet in cancer therapy
› IATROGENISITET
› https://doi.org/10.1111/eci.12834 How to survive the medical misinformation mess
› https://doi.org/10.1111/jlme.12068 Institutional Corruption of Pharmaceuticals and the Myth of Safe and Effective Drugs
› https://doi.org/10.1136/bmj.f3830 Why we can’t trust clinical guidelines
› https://doi.org/10.1016/S0140-6736(15)60696-1 Offline: What is medicine's 5 sigma?
› https://apjcn.nhri.org.tw/server/apjcn/procnutsoc/1990-1999/1995/1995%20p1-10.pdf
Last ned episoden
Innspilt: 2023-07-18
Publisert: 2023-07-28
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