Big 12 Week 5 Predictions: Spread Picks, Previews & Upsets

It’s Week 5 of the 2025 Big 12 football season! Pete Mundo of Heartland College Sports previews every matchup on the schedule and gives his best picks against the spread. From the biggest conference showdowns to potential upsets, here’s everything you need to know heading into this weekend.

👉 Join the conversation in our forums: https://www.heartlandcollegesports.com/forums/

🛒 Grab your HCS gear here: https://hcs.myswaggymerch.com/#!/

Privacy & Opt-Out: https://redcircle.com/privacy