With a history extending back millennia, with a biology that leads to permanent disability for tens of millions of people globally, and with a bacterial endosymbiont that may prove to be its Achilles heel, the filarial parasites that cause lymphatic filariasis are quite the complex creatures. In this episode, we explore the intricacies of this neglected tropical disease - also known as elephantiasis. We start by examining its complicated ecology involving many mosquito and parasite species, before moving on to its tricky biology where we finally answer the age-old question, “What is the lymphatic system anyway?”. Next, we move on to the convoluted history of lymphatic filariasis, where it holds the distinction of being the first disease recognized as mosquito-borne. We wrap up the episode with a look at its present global status, grappling with some current figures on the tremendous global burden of this disease and investigating some exciting treatment developments that will hopefully bring relief to the hundreds of millions of people at risk of developing this debilitating disease.
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Ep 111 RSV: What’s syncytial anyway?
Ep 110 Influenza, Take 2: Fowl Play
Ep 109 Chikungunya: Not dengue (or is it?)
Ep 108 Gout: Toetally fascinating
Ep 107 Sepsis: It's a mess
Ep 106 Turner Syndrome: Let's talk about X
Ep 105 Down in the Mumps
Ep 104 The Bends: Industrial Revolution, baby
Ep 103 Leptospirosis: Don't blame the rats
Ep 102 Arsenic: Paris Green with Envy
Ep 101 Immortality: This Podcast Won't Kill You
Ep 100 Monkeypox: Here we go again?
Ep 99 Salmonella: A hard egg to crack
Ep 98 Folate: Marmite, anyone?
Special Episode: Snake Venom Evolution
Ep 97 Snake Venom: Collateral Damage
Special Episode: Coprolites!
Ep 96 Tapeworm: We encyst you listen
Special Episode: On the Origin of Epidemiology
Ep 95 Tetanus: An inhuman calamity!
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