With a history extending back millennia, with a biology that leads to permanent disability for tens of millions of people globally, and with a bacterial endosymbiont that may prove to be its Achilles heel, the filarial parasites that cause lymphatic filariasis are quite the complex creatures. In this episode, we explore the intricacies of this neglected tropical disease - also known as elephantiasis. We start by examining its complicated ecology involving many mosquito and parasite species, before moving on to its tricky biology where we finally answer the age-old question, “What is the lymphatic system anyway?”. Next, we move on to the convoluted history of lymphatic filariasis, where it holds the distinction of being the first disease recognized as mosquito-borne. We wrap up the episode with a look at its present global status, grappling with some current figures on the tremendous global burden of this disease and investigating some exciting treatment developments that will hopefully bring relief to the hundreds of millions of people at risk of developing this debilitating disease.
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Ep 42 Dandy Dengue Fever
Ep 41 Ricin: A Bad Seed
Ep 40 Dancing Plague: Worst Dance Party Ever
Ep 39 Toxoplasmosis: Calling All Cats
Ep 38 Lead Poisoning: Heavy Metal Episode
Ep 37 E. coli (unless it's beets)
Ep 36 Shades of Syphilis
Ep 35 Lyme Disease: I'd like to check you for ticks
Ep 34 Cystic Fibrosis: Complete Somatic Rebellion
Ep 33 Chytrid: The Silent Forest
Ep 32 Ask the Erins
Ep 31 Giardia: Gerardia
Ep 30 Encephalitis Lethargica: Sleep Perchance to Dream (& Dream & Dream)
Ep 29 Aspirin the Wonder Drug: Crossover w/ IDOP
Ep 28 H. pylori: Don't try this at home
Ep 27 Vaccines Part 2: Have you thanked your immune system lately?
Ep 26 Vaccines part 1: Let's hear it for Maurice
Ep 25 Put your hands together for: Gonorrhea!
Ep 24 Zika: Rumors and Rumours
Ep 23 Opening a can of Hookworms
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