Paul Offit is a pediatrician specializing in infectious diseases and an expert in virology and vaccine development. He currently serves on the FDA committee evaluating COVID-19 vaccines. In this episode, Paul’s second appearance on The Drive, he provides an update on all the SARS-CoV-2 vaccines currently deployed, explains why the concerns raised around the mRNA vaccines are not legitimate, and offers his view on the prospects and timeframe of reaching herd immunity. He also takes a deep dive into immunology, explaining the short-term and long-term immune response to both natural infection and vaccination and how these two can function together to provide durable immunity. Additionally, they discuss the theories on the origins of this virus, what impact the new COVID-19 variants might have, and the recent pausing of the J&J vaccine. Finally, they discuss how we can be better prepared for an inevitable future outbreak of a novel virus. This episode was originally recorded on April 14, 2021.
We discuss:
Overview and current status of the SARS-CoV-2 vaccine strategies [4:10];
Addressing concerns about mRNA vaccines [9:00];
How the failure to make an effective HIV vaccine aided the development of a COVID-19 vaccine [16:45];
Where SARS-CoV-2 falls on the spectrum of its ability to mutate and what that means for immunity and vaccination [21:30];
How the combination of short-term and long-term immune response to SARS-CoV-2 work together to provide durable immunity [28:00];
Importance of understanding relative vs. absolute risk reduction [38:15];
Implications of pausing the J&J vaccine due to reports of blood clotting in the brain [42:45];
What constitutes herd immunity and the concerns of rising vaccine hesitancy [47:45];
When we might reach herd immunity, future vaccines for children, and long-term outlook for maintaining population immunity [58:45];
Theories about the origins of SARS-CoV-2 [1:07:00];
Preparing for the possibility of a future pandemic and how we can learn from our mistakes [1:10:40]; and
More.
Learn more: https://peterattiamd.com/
Show notes page for this episode: https://peterattiamd.com/pauloffit2
Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/
Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/
Connect with Peter on Facebook | Twitter | Instagram.
#208 - Tragedy, grief, healing, and finding happiness | Kelsey Chittick
#207 - AMA #35: "Anti-Aging" Drugs — NAD+, metformin, & rapamycin
#206 - Exercising for longevity: strength, stability, zone 2, zone 5, and more
#205 - Energy balance, nutrition, & building muscle | Layne Norton, Ph.D. (Pt.2)
#204 - Centenarians, metformin, and longevity | Nir Barzilai, M.D.
#203 - AMA #34: What Causes Heart Disease?
#202 - Peter on nutrition, disease prevention, sleep, and more — looking back on the last 100 episodes
In remembrance of Sarah Hallberg, D.O., M.S. (Ep. #162 Rebroadcast)
#201 - Deep dive back into Zone 2 | Iñigo San-Millán, Ph.D. (Pt. 2)
#200 - AMA #33: Hydration—electrolytes, supplements, sports drinks, performance effects, and more
#199 - Running, overcoming challenges, and finding success | Ryan Hall
#198 - Eye health—everything you need to know | Steven Dell, M.D.
#197 - The science of obesity & how to improve nutritional epidemiology | David Allison, Ph.D.
#196 - AMA #32: Exercise, squats, deadlifts, BFR, and TRT
#195 - Freedom, PTSD, war, and life through an evolutionary lens | Sebastian Junger
#194 - How fructose drives metabolic disease | Rick Johnson, M.D.
#193 - AMA #31: Heart rate variability (HRV), alcohol, sleep, and more
#192 - COVID Part 2: Masks, long COVID, boosters, mandates, treatments, and more
#191 - Revolutionizing our understanding of mental illness with optogenetics | Karl Deisseroth M.D., Ph.D.
#190 - Paul Conti, M.D.: How to heal from trauma and break the cycle of shame
Create your
podcast in
minutes
It is Free
Huberman Lab
The Relaxback UK Show
Good Nurse Bad Nurse
On Call With Dr. Anselm Anyoha
The Doctor’s Farmacy with Mark Hyman, M.D.