Many studies have linked proton pump inhibitor (PPI) use to several adverse effects including Clostridium difficile-associated diarrhea, community-acquired pneumonia, bone fractures, and nutritional deficiencies. Other reports have linked PPI use with chronic kidney disease, cognitive decline, myocardial infarction (MI), stroke, and even death. Many patients take PPIs chronically and may be concerned about the risk of these side effects. This poses a challenge for healthcare providers as safety data has been primarily based on retrospective and observational studies. A recently pre-planned analysis using data from the prospective COMPASS study sheds some reassuring light.
Guest Authors: Hindu Rao, PharmD and Jelena Lewis, PharmD, BCACP, APh
Music by Good Talk
An Aspirin a Day to Prevent Colon CA
The Heart of the Matter – Is EMPA-REG a Game Changer for Diabetes Management?
Taking a CHANCE on Clopidogrel Plus Aspirin to Prevent Stroke Recurrence
How Long Is Long Enough? Extending OAC After Unprovoked PE
Managing Direct Oral Anticoagulants – What’s Our Role?
PCSK9 Inhibitors: Blockbusters or Bust?
Short-Course Dexamethasone for Asthma Exacerbations in Children
CVD Risk Scores - Are They Accurate?
Folic Acid: A Simple Answer to a Very Large Problem?
Dressed for Success? Professional Attire and Patient Perceptions
Insulin Delivery in Type 2 Diabetes: To Pump or Not to Pump?
Intensive Antiplatelet Therapy - Is Extended Therapy Worth It?
Co-trimoxazole+RAAS Inhibitors: A Deadly Combination?
Anticoagulation Bridge Therapy - Risks and Benefits Examined
Fish Oil for Rheumatoid Arthritis
Home-Based Primary Care: Can We Take These Results to the Bank?
Community Health Workers to Improve Asthma Outcomes
Potential Uses of Niacin: Flushing Out The Results of HPS2-THRIVE
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