Regenerative medicine: Game changing innovation or the next big flop? Episode #360

Host Dr. Devin McFadden, MD is joined by Dr. Lisa Fortier, DVM, PhD on the AMSSM Sports Medcast to discuss regenerative medicine technologies and the current evidence for their use. Dr. Fortier is a Professor of Surgery at Cornell University, College of Veterinary Medicine in Ithaca, New York, with a particular interest in translational research including the prevention of post- traumatic osteoarthritis. In addition, her internationally renowned research investigates the clinical application of stem cells and biologics such as platelet-rich plasma and bone marrow concentrate for cartilage repair and tendinosis. In this 15 minute conversation Dr. Fortier addresses the following topics: What are orthobiologics and regenerative medicine? What is the evidence behind their use? What current research is being conducted in this field? Where she see the field in 5-10 years. IOC Consensus on Use of PRP in Sports Medicine- https://bjsm.bmj.com/content/44/15/1072 Engebretsen L, Steffen K, Alsousou J, et al. IOC consensus paper on the use of platelet-rich plasma in sports medicine. Br J Sports Med. 2010;44:1072-1081. Systematic Review of Stem Cell Use in Tendon Injuries- https://bjsm.bmj.com/content/51/13/996 Pas HIMFL, Moen MH, Haisma HJ, et al. No evidence for the use of stem cell therapy for tendon disorders: a systematic review. Br J Sports Med. 2017;51:996-1002. Role of platelet-rich plasma in articular cartilage injury and disease- https://www.thieme-connect.com/DOI/DOI?10.1055/s-0034-1384672

Mascarenhas R, Saltzman BM, Fortier LA, et al. Role of platelet rich plasma in articular cartilage injury and disease. J Knee Surg. 2015 Feb;28(1):3-10