In the battle to defeat cancer, award-winning UHN researcher Dr. Mathieu Lupien is a modern-day version of the Bletchley Park World War Two codebreakers. Dr. Lupien searches the human genome, trying to crack the origin of how and why cancer starts. He knows deciphering that enigmatic code is one of the keys that will lead to a cure for cancer. He explains how the human genome is like a road map to the inner workings of what makes us, well, us—and the many ways cancer disrupts that journey, and why researchers are now looking at so-called “junk DNA” for the source to cancer’s origins.
Dr. Lupien also talks about the Terry Fox loonie he carries in his pocket at all times as a reminder of the commitment and importance of the work done in his lab, how a line in a TV show he watched as a child in Quebec has fuelled his research career,” and his advice for kids who want to go into science.
Dr. Andrea Furlan on groundbreaking new treatments for chronic pain
Check out UHN’s Krembil Brain Institute podcast, Your Complex Brain
Behind the Breakthrough Special Edition - ”UHN Oral History Project’” with Dr Alan Hudson
Behind the Breakthrough Special Edition - ”UHN Oral History Project” with Dr. Bernie Langer
Dr. Angela Cheung pioneers research on the symptoms and treatment for long hauler Covid patients
Dr. Andres Lozano on investigating DBS to treat Alzheimer’s disease
Dr. Babak Taati on pioneering the use of computer vision to help seniors live safer, healthier lives.
Dr. Joan Wither on searching for the genetic and immune system abnormalities that lead to systemic autoimmune rheumatic diseases
Dr. Gang Zheng on harnessing the promise of nanotechnology for the detection and treatment of cancer
Dr. Jordan Feld on shifting from discovering a pill that cures Hepatitis C to investigating a treatment for mild COVID
Dr. Catherine O’Brien on the world-first discovery that colorectal cancer cells hibernate like bears to evade chemotherapy
Dr. Deepali Kumar on the world first discovery that 3rd dose of COVID Vaccine significantly boosts protection against the coronavirus for transplant patients
Dr. Beate Sander on the economics of infectious diseases and guiding public health policy during the Covid-19 pandemic.
BTB Season 3 Special Edition with Dr. Brad Wouters, UHN EVP of Science and Research
Dr. John Dick on his famous discovery of cancer stem cells, and the puzzle of research
Dr. Mansoor Husain on breakthrough drug for diabetes and heart disease
Dr. Alex Mihailidis on helping us live at home longer
Dr. Ralph DaCosta on a better way to visualize cancer and his serendipitous invention
Dr. Sonya MacParland on developing the world’s first map of the liver
Dr. Heather Baltzer on pioneering hand trauma treatment.
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