What if the future of antimicrobial discovery lies buried in medieval manuscripts? In this episode of Foodie Pharmacology, Dr. Cassandra Quave speaks with microbiologist Dr. Freya Harrison of the University of Warwick about the emerging field of “Ancient-biotics”. They examine how early medieval remedies such as Bald’s eyesalve are being reconstructed and tested against modern antibiotic-resistant biofilms. Dr. Harrison explains how her lab builds infection models that mimic the human body, why biofilms are so difficult to treat, and how combinations of natural products like honey and vinegar may hold clues to new antimicrobial strategies. This conversation bridges microbiology, Medieval texts, and pharmacology showcasing how historical knowledge can still inform modern medicine.