Clinical Perspectives: Can a Vitamin or Antioxidant a Day Keep the Sepsis Away?

There has been a renewed interest in managing COVID-19 patients with septic shock and the use of vitamins and anti-oxidants such as Vitamin C and Zinc. Listen to our 2018 Midyear Clinical Meeting presentation by Craig Whitman and Lee Skrupky as they describe the mechanisms of action, toxicities, and pharmacokinetic considerations of vitamin C, thiamine, selenium, zinc and vitamin E in sepsis. They evaluate the literature describing the effect of vitamin or antioxidant supplementation on outcomes in patient with sepsis. The core concepts from this presentation can help pharmacists recommend appropriate vitamin or antioxidant supplements in patients with sepsis.