The Gary Null Show - 11.10.22

Videos:

1. Society is going to COLLAPSE -Neil Oliver ( 5:24)
2. Fear Psychosis and the Cult of Safety – Why are People so Afraid?  – Academy of Ideas (13:25)
3. The Great Reset and Transhumanism | Beyond the Cover (17:50)
4. We can be Brainwashed if allowed (Macdonald)
5. MEP Clare Daly calls out EU on wanting to supply arms to Ukraine but not Palestine or Yemen

Antioxidants may reduce oxidative stress in men with prostate cancer

Universities of Connecticut, Louisiana State, North Carolina, South Carolina, and California , November 3, 2022

This latest paper – which looked at men with prostate cancer from the North Carolina-Louisiana Prostate Cancer Project – came in light of a growing body of evidence suggesting oxidative stress plays a role in the development and progression of prostate cancer. The researchers looked at biomarkers of oxidative stress in the blood, urine and prostate tissue. 

They found a greater antioxidant intake was associated with lower urinary 8-isoprostane concentrations. 

A 10% increase in antioxidant intake saw an unadjusted 1.1% decrease in urinary 8-isoprostane levels. 

8-Isoprostane has been described as a “reliable marker”  and recognised  “gold standard” for lipid peroxidation – the oxidative degradation of lipids. 

“This study demonstrated that intake of antioxidants was associated with less oxidative stress among men with incident prostate cancer,” the researchers concluded in the British Journal of Nutrition.   

“The results of this study and others warrant additional research in humans on the mechanisms underlying the relationship between dietary antioxidants and prostate tissue redox status and carcinogenesis, as well as determining whether this relationship may influence disease severity, progression and recurrence.” 

High-intensity exercise changes how muscle cells manage calcium 

Karolinska Institute (Sweden) November 2, 2022

Researchers at Karolinska Institutet in Sweden have discovered a cellular mechanism behind the surprising benefits of short, high-intensity interval exercise. Their findings, which are published in the scientific journal PNAS, also provide clues to why antioxidants undermine the effect of endurance training. 

A few minutes of high-intensity interval exercise is enough to produce an effect at least equivalent to that achieved with traditional much more time-consuming endurance training. High-intensity exercise has become popular with sportspeople and recreational joggers alike, as well as with patients with impaired muscle function. However, one question has so far remained unanswered: how can a few minutes’ high-intensity exercise be so effective?

To investigate what happens in muscle cells during high-intensity exercise, the researchers asked male recreational exercisers to do 30 seconds of maximum exertion cycling followed by four minutes of rest, and to repeat the procedure six times. They then took muscle tissue samples from their thighs.

“Our study shows that three minutes of high-intensity exercise breaks down calcium channels in the muscle cells,” says Professor Håkan Westerblad, principal investigator at Karolinska Institutet’s Department of Physiology and Pharmacology. “This causes a lasting change in how the cells handle calcium, and is an excellent signal for adaptation, such as the formation of new mitochondria.”

Mitochondria are like the cell’s power plants, and changes that stimulate the formation of new mitochondria increase muscle endurance. What the researchers found was that the breakdown of calcium channels that was triggered by the high-intensity exercise was caused by an increase in free radicals, which are very reactive and oxidise cellular proteins.

The cells therefore have antioxidative systems for trapping and neutralising the radicals. Antioxidants, like vitamins E and C, are also present in food and are common ingredients in dietary supplements. In the present study, the researchers examined what happens when isolated mouse muscles are treated with an antioxidant before and after simulated high-intensity interval exercise.

“Our study shows that antioxidants remove the effect on the calcium channels, which might explain why they can weaken muscular response to endurance training,” says Professor Westerblad. “Our results also show that the calcium channels aren’t affected by the three minutes of high-intensity interval exercise in elite endurance athletes, who have built up more effective antioxidative systems.” 

8 Weeks Of Mindfulness Training Can Lower Blood Pressure For Months

Brown University, November 8, 2022

A custom mindfulness program which teaches people how to have healthy relationships with their diet, physical activity, alcohol use, and stress can help lower blood pressure for at least six months, a new study finds.

A team with the American Heart Association found that eight weeks of mindfulness training significantly lowers systolic blood pressure readings — the top number in a blood pressure measurement. The training focused on attention control, meditation, self-awareness, and emotion regulation, using weekly group sessions and daily mindfulness exercises.

“Mindfulness is non-judgmental, present-moment awareness of physical sensations, emotions and thoughts,” says lead study author Eric Loucks, Ph.D., an associate professor of epidemiology and director of the Mindfulness Center at Brown University, in a media release.

“It is almost like a scientist curiously and objectively observing the information coming in through the sense organs and the mind, and then responding skillfully to that information. Mindfulness also involves the concept of remembering, or in other words, remembering to bring one’s wisdom (wherever it was gained, such as from health care professionals or public health messages) into the present moment. Wisdom in the context of elevated blood pressure levels may include knowledge that evidence-based practices, such as physical activity, diet, limited alcohol consumption and antihypertensive medication adherence, can improve well-being.”The participant group included over 200 adults from the Providence, Rhode Island area who all had high blood pressure, meaning their readings were higher than 120 mm Hg systolic or 80 mm Hg diastolic blood pressure (the bottom number). Nearly six in 10 were women (59%) and had an average age of 59.

Results show the Mindfulness-Based Blood Pressure Reduction group saw their systolic blood pressure drop by an average of 5.9 mm Hg. Those using enhanced usual care only saw their blood pressure drop by 1.4 mm Hg. While systolic blood pressure changed, neither group saw their diastolic blood pressure drop.

In addition to improving their blood pressure, the mindfulness group also engaged in far fewer sedentary activities over the six months. Those in mindfulness training reduced their sedentary sitting by an average of 351 minutes each week. Those doing mindfulness training were also more likely to eat a heart-healthy diet and experienced less stress during the course of the study.

Grapefruit Juice Supports Healthy Arteries 

French National Institute for Agricultural Research, November 2022

Want to hydrate your way toward a healthier heart? Then you may want to consider adding grapefruit juice into your diet.

Because a recent study found that grapefruit juice enriched with the flavonoid naringenin actually improved a marker associated with arterial function.

The results of the study were published in the American Journal of Clinical Nutrition.

Previous research shows citrus bioflavonoids support blood vessel function. They strengthen blood vessel walls, decrease bruising, prevent bleeding, and heal hemorrhoids (hemorrhoids are swollen veins). Of the group of citrus bioflavonoids, naringenin stands out.

For the current study, 48 healthy post-menopausal women were recruited and assigned to drink grapefruit juice or a drink without flavonoids for 6 months. The grapefruit juice contained 210 mg of naringenin glycosides.

According to the results of the study, the women drinking the grapefruit juice showed a lower carotid femoral pulse wave velocity, indicating a reduction in arterial stiffening.

Naringenin is also found in oranges and tomatoes. It’s also available as a dietary supplement and is usually found in citrus bioflavonoid formulas.

Low levels of air pollution deadlier than previously thought

McGill University, November 7, 2022

The World Health Organization’s most recent estimates (2016) are that over 4.2 million people die prematurely each year due to long-term exposure to fine particulate outdoor air pollution (often referred to as PM2.5). A recent study involving McGill researchers now suggests that the annual global death toll from outdoor PM2.5 may be significantly higher than previously thought. That’s because the researchers found that mortality risk was increased even at very low levels of outdoor PM2.5, ones which had not previously been recognized as being potentially deadly. These microscopic toxins cause a range of cardiovascular and respiratory diseases and cancers.

“We found that outdoor PM2.5 may be responsible for as many as 1.5 million additional deaths around the globe each year because of effects at very-low concentrations that were not previously appreciated,” said Scott Weichenthal, an Associate Professor at McGill University and the lead author on the recent paper in Science Advances.

The researchers arrived at this conclusion by combining health and mortality data for seven million Canadians gathered over a twenty-five-year period with information about the levels of outdoor PM2.5 concentrations across the country.

The WHO recently set out ambitious new guidelines for annual average outdoor fine particulate air pollution, cutting its earlier recommendations in half, from concentrations of 10 to concentrations of 5 micrograms (ug) per cubic meter. The current United States Environmental Protection Agency standard of 12 (ug) per cubic meter is now more than double the value recommended by the WHO.

Highly processed foods can be considered addictive like tobacco products, study claims

University of Michigan & Virginia Tech University, November 9, 2022

Can highly processed foods be addictive?

A new University of Michigan and Virginia Tech analysis took the criteria used in a 1988 U.S. Surgeon General’s report that established that tobacco was addictive and applied it to food. 

Based on the criteria set for tobacco, the findings indicate that highly processed foods can be addictive, said lead author Ashley Gearhardt, U-M associate professor of psychology, and Alexandra DiFeliceantonio, assistant professor at Fralin Biomedical Research Institute at Virginia Tech. 

In fact, the addictive potential for food such as potato chips, cookies, ice cream and French fries may be a key factor contributing to the high public health costs associated with a food environment dominated by cheap, accessible and heavily marketed highly processed foods, the researchers said. 

The research, published in the current issue of Addiction, offers evidence that highly processed foods meet the same criteria used to identify cigarettes as an addictive substance: 

• They trigger compulsive use where people are unable to quit or cut down (even in the face of life-threatening diseases like diabetes and heart disease)
• They can change the way we feel and cause changes in the brain that are of a similar magnitude as the nicotine in tobacco products
• They are highly reinforcing
• They trigger intense urges and cravings 

DiFeliceantonio said the ability of highly processed foods to rapidly deliver unnaturally high doses of refined carbohydrates and fat appear key to their addictive potential.

Highly processed foods contain complex substances that cannot be simplified to a single chemical agent acting through a specific central mechanism. The same can be said for industrial tobacco products, which contain thousands of chemicals including nicotine, Gearhardt said.

Poor diets dominated by highly processed foods now contribute to preventable deaths on par with cigarettes. Similar to tobacco products, the food industry designs their highly processed foods to be intensely rewarding and hard to resist, the researchers said.