Inherited Diseases with Dr. Dave Steffan

In this episode of "DocTalk," we join Dr. Dan Thomson and Dr. Dave Steffen at the University of Nebraska in Lincoln to delve into pathology in cattle, particularly inherited diseases. Dr. Steffen, with over 35 years of experience, specializes in perinatal issues, investigating birth defects and inherited diseases in cattle. He collaborates closely with major breed associations like Hereford, Angus, Simmental, and Red Angus, often serving as a go-to expert when issues arise, especially with sire-related concerns.

When cattle owners suspect an issue, they typically involve a local veterinarian, who may then contact Dr. Steffen. Utilizing digital technology, veterinarians can share images or videos for initial assessment, potentially saving the need for transporting animals over long distances. Dr. Steffen's work spans a broad spectrum, from investigating diseases caused by environmental factors to researching one-off mutations occurring in early embryos, often necessitating complex genetic analysis.

One ongoing project involves investigating hydrops pregnancies in Simmental cattle, a condition characterized by severe abdominal enlargement in mid-gestation. This research is crucial for the breed due to its devastating impact. Dr. Steffen's lab actively collaborates with breed associations and welcomes reports and samples, particularly from purebred animals, to further their understanding of inherited diseases.

Throughout the episode, the emphasis is on collaboration between cattle owners, veterinarians, and research institutions like the University of Nebraska's Veterinary Diagnostic Lab. By leveraging expertise and resources, they aim to address emerging issues and advance knowledge in bovine pathology.