Scientists often refer to DNA as the blueprint of a cell. Whether the genetic material is single stranded or double stranded, linear or circular, organisms across the tree of life rely on their genomic blueprint for instructions on living, growing, and reproducing. Due to the amount of information carried by this blueprint, the size of the genome poses a biological dilemma; from humans to single-celled aquatic organisms, all eukaryotes must find a solution for organizing their DNA into a tiny nuclear space. In the quest for better tools to understand the 3D genomic architecture and the biological challenge of chromosome folding, a team of biochemistry and systems biology researchers investigated the unique genomic organization of unicellular marine plankton, dinoflagellates.
In this episode, Deanna MacNeil from The Scientist’s Creative Services Team spoke with Job Dekker, a systems biology professor at the University of Massachusetts Chan Medical School and an investigator at the Howard Hughes Medical Institute, to learn more.
The Scientist Speaks is a podcast produced by The Scientist’s Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research. This month's episode is sponsored by Arima Genomics.
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The Epigenetic Origins of Allergy and Asthma
The Long Haul: Improving Cardiac Cell Therapy Persistence
Decoding Smell: Demystifying Human Disease and Behavior
Cancer Immunotherapy: CRISPR Reveals Targets In Vivo
A Path Back to Health: Immune Tolerance to Infectious Disease
Repurposing Living Systems to Fight a Pandemic: Synthetic biologists repurpose cellular machinery to fight COVID-19
Bonus LabTalk Episode: Myeloid Cells in Cancer and Science Advocacy: A Conversation with Miriam Merad
Experimental Cures for Fragile Patients: Prenatal Stem Cell and Gene Therapies
A Game of Cancer and Evolution: Scientists leverage the principles of evolution to outwit cancer at its own game
Brains in the Palm of Your Hand: 3D Organoid Cell Culture
Unusually Wired: Human Brains are Attuned to Appreciate Musical Pitch
Hidden Hitchhikers: Lessons Learned from The Human Microbiome Project
Tackling Antibiotic Resistance: Viruses to the Rescue
The Buzz About Genetically Modified Mosquitoes
Birds on the Brain: The Neuroscience Behind Songbird Communication and the Human Brain
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