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In this episode, the hosts delve into the fascinating connections between exercise, glucose consumption, and the reduced incidence of cancer. They highlight recent peer-reviewed studies showing how high intensity aerobic exercise can act as a 'metabolic shield' in distant organs, blocking cancer progression and metastatic dissemination. The discussion includes a comparison of human and animal data, demonstrating that physical activity significantly reduces metastatic tumor growth. The episode also touches on Alzheimer's disease and various contributing factors, proposing that metabolic health is key in preventing both neurodegenerative diseases and cancer. The hosts emphasize the importance of holistic lifestyle changes, including diet, exercise, and stress management, to achieve long-term health benefits.