Markus Gruell, Autolus Therapeutics

In this episode of Careers in Discovery, we’re joined by Markus Gruell, Senior Vice President of Corporate Quality at Autolus, one of the UK’s leading CAR-T therapy pioneers.

Markus takes us behind the scenes of Autolus’ journey from a UCL spinout to a commercial-stage Biopharma company, offering a rare look at how quality underpins every part of the drug development lifecycle. From working across GMP and GCP to collaborating with regulators on novel therapies, Markus shares what it means to lead quality in a fast-moving, high-growth Biotech business.

We also explore Markus’ personal journey - from pharmacist to QP, and from the NHS to senior leadership - guided by a passion for learning, a commitment to patient safety, and a belief in empowering his team through empathy and integrity.

If you're curious about CAR-T, what quality looks like in a next-gen therapy company, or how to build a meaningful leadership career without a traditional plan, this episode is not to be missed.