SENTOR Study: SLN in High-Risk Endometrial Cancer with Sarah Ferguson

Dr. Ferguson is a Professor in the Division of Gynecologic Oncology in the Department of Obstetrics and Gynecology at the University of Toronto and a member of the Division of Gynecologic Oncology at University Health Network/Sinai Health Systems. She is the Director of Research for the Division of Gynecologic Oncology at Princess Margaret Cancer. Dr. Ferguson completed her residency in Obstetrics and Gynecology at University of Toronto and a fellowship at Memorial Sloan-Kettering Cancer Centre in Gynecologic Oncology. Current research program includes prospective surgical trials in cervical and endometrial cancer, evaluation of patient reported outcomes and molecular characterization of endometrial cancer. Highlights: + Diagnostic accuracy of SLN technique is excellent in high grade endometrial cancer – high sensitivity (low false negative rate), high NPV , DR and bilaterality rate + Based on this is a viable option to surgical staging in this population (clinical stage 1, high grade endometrial cancer)

+ High proportion (26%) of node positive would be missed if SLN technique was not performed