JNP Micro Podcasts: Reflex interactions on action potential subpopulations

In this episode of the Journal of Neurophysiology's Podcast Series, coauthor Natasha G. Boyes delves into her recently published research, "Interaction of Simultaneous Hypoxia and Baroreflex Loading on Control of Sympathetic Action Potential Subpopulations." This study explores the complex interaction between baroreflex loading and peripheral chemoreflex activation in regulating the sympathetic nervous system. Dr. Boyes explains how chemoreflex activation buffers baroreflex-induced reductions in sympathetic activity and reveals that baroreflex loading significantly alters sympathetic action potential clusters, even in the presence of chemoreflex signals. Tune in to hear how this research provides new insights into the dominant role of the arterial baroreflex in controlling medium-sized sympathetic neurons amidst competing stressors.

 

Interaction of simultaneous hypoxia and baroreflex loading on control of sympathetic action potential subpopulations

Natasha G. Boyes, Stephen A. Klassen, Sarah E. Baker, Wayne T. Nicholson, Michael J. Joyner, J. Kevin Shoemaker, and Jacqueline K. Limberg

Journal of Neurophysiology 2024 132:3, 1087-1097