Nitric oxide, prostanoids, and oxygen consumption in the human skeletal muscle

Another exciting installment in our AJP-Heart and Circ podcast series takes us to the icy climes of Finland to discuss the article by Heinonen et al regarding NO regulation of muscle blood flow and metabolism using heroic PET studies. Joining our Editor in Chief William C. Stanley is lead author Ilkka Heinonen (University of Turku, Finland) and expert Michael Joyner (Mayo Clinic). Heinonen Ilkka, Saltin Bengt, Kemppainen Jukka, Hannu T. Sipilä, Oikonen Vesa, Nuutila Pirjo, Knuuti Juhani, Kalliokoski Kari, and Hellsten Ylva. Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a PET study with nitric oxide and cyclooxygenase inhibition. Am J Physiol Heart Circ Physiol 300: H1510-H1517, 2011.