Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension

A novel and unique large animal model illuminates why we should focus, for a change, on right ventricular cardiac disease and some of the changes that occur during development of right ventricular failure and pulmonary hypertension. Associate Editor Meredith Bond interviews authors Lori Walker and Peter Buttrick (both University of Colorado Denver), as well as leading expert JP Jin (Wayne State University) about this innovative study presented in the article by Walker et al.

Lori A. Walker, John Stephen Walker, Amelia Glazier, R. Dale Brown, Kurt R. Stenmark, and Peter M. Buttrick.Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension Am J Physiol Heart Circ Physiol, published online ahead of print May 27, 2011; doi:10.1152/ajpheart.00249.2011.