Right Ventricular Arrhythmogenic Remodeling in Heart Failure

Can translational research using donated human hearts uncover the mechanism behind cardiac sudden death in heart failure patients? In our latest podcast, Editor in Chief William Stanley interviews renowned researcher Igor Efimov (Washington University) and global expert Kenneth Laurita (Case Western Reserve University) about the latest work by Lou et al. demonstrating enhanced dispersion of repolarization in right ventricles obtained from heart failure patients.

Qing Lou, Deborah L Janks, Katherine Holzem, Di Lang, Birce Onal, Christina M Ambrosi, Vadim V Fedorov, I-Wen Wang, and Igor R. Efimov Right Ventricular Arrhythmogenesis in Failing Human Heart: The Role of Conduction and Repolarization Remodeling Am J Physiol Heart Circ Physiol, published online October 5, 2012, doi: 10.1152/ajpheart.00457.2012.