Should We Use Preferred Pronouns When Not Sure of a Person’s Biological Sex?

Questions about using a person’s preferred pronouns when we’re not sure of their biological sex and whether we should ask why our employer is requesting we use pronouns in our email signature in case the purpose is to help people who are unfamiliar with English names know what sex we are.

• What should I do about using a person’s preferred pronouns when it’s not clear what that person’s sex actually is?
• Since including pronouns may be helpful to immigrants who aren’t familiar with English names, if requested to include pronouns in an email signature, must we always ask why?