JNP Micro Podcasts: Beadex is required in Neurons

In this podcast coauthor Kripa Chitre discusses the recently published article titled "Beadex, the Drosophila LIM only protein, is required for the growth of the larval neuromuscular junction."  A novel role for Beadex (Bx) regulates the larval neuromuscular junction (NMJ) structure and function in a tissue-specific manner. Bx is expressed in a subset of Toll-6-expressing neurons and is involved in regulating synaptic span and physiology, possibly through its negative interaction with Highwire (Hiw). The findings of this study provide insights into the molecular mechanisms underlying NMJ development and function and warrant further investigation to understand the role of Bx in these processes fully.

 

Article Citation:

Beadex, the Drosophila LIM only protein, is required for the growth of the larval neuromuscular junction

Kripa Chitre, Subhash Kairamkonda, Manish Kumar Dwivedi, Saumitra Yadav, Vimlesh Kumar, Sujit K. Sikdar, and Upendra Nongthomba

Journal of Neurophysiology 2024 132:2, 418-432