Food Allergy Treatment: A Paradigm Shift to Proactive Therapies

This source offers a comprehensive overview of food allergy management, detailing a paradigm shift from reactive avoidance to proactive therapeutic interventions as of August 2025. It explains the IgE-mediated immune response underlying food allergies and distinguishes it from food intolerance, while also outlining the spectrum of clinical manifestations from mild symptoms to life-threatening anaphylaxis. The text highlights the foundational standard of care, emphasizing strict allergen avoidance and the critical role of epinephrine in emergencies, even as it introduces innovative treatments like oral immunotherapy (OIT), epicutaneous immunotherapy (EPIT), and groundbreaking biologic agents such as omalizumab and dupilumab. Finally, the source explores the robust research and development pipeline, including microbiome-modulating therapies and gene therapy, acknowledging the challenges of cost, access, and implementation in integrating these advances into clinical practice and emphasizing the vital role of patient advocacy organizations and research centers.

Research done with the help of artificial intelligence, and presented by two AI-generated hosts.