This report provides a comprehensive examination of Antisocial Personality Disorder (ASPD), clarifying its relationship with the more commonly used, though unofficial, terms psychopathy and sociopathy. It explains that while ASPD is the clinical diagnosis in the DSM-5, psychopathy is often seen as a neurodevelopmental condition with biological roots and a complete lack of empathy, whereas sociopathy is considered to be more influenced by environmental factors and trauma, with a limited capacity for emotional connection. The text outlines diagnostic criteria for ASPD, discusses neurological differences in the brains of psychopaths, and illustrates these concepts through real-world and fictional case studies of individuals exhibiting antisocial traits. Finally, the report offers practical strategies for recognizing manipulative behaviors and protecting oneself from those with these challenging personality structures.